Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2617556..2617701 Replicon chromosome
Accession NZ_CP074558
Organism Klebsiella pneumoniae strain S39_CRE40

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2617563..2617665 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2617556..2617701 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHW03_RS13110 (KHW03_13070) 2613088..2614521 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KHW03_RS13115 (KHW03_13075) 2614637..2614876 + 240 WP_002911393.1 YebV family protein -
KHW03_RS13120 (KHW03_13080) 2614974..2615165 + 192 WP_002911395.1 YebW family protein -
KHW03_RS13125 (KHW03_13085) 2615162..2615815 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
KHW03_RS13130 (KHW03_13090) 2615972..2616940 + 969 WP_004151446.1 VirK/YbjX family protein -
KHW03_RS13135 (KHW03_13095) 2617045..2617188 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2617556..2617701 + 146 - - Antitoxin
- 2617563..2617665 - 103 - - Toxin
KHW03_RS13140 (KHW03_13100) 2617824..2618162 - 339 WP_002911404.1 YebY family protein -
KHW03_RS13145 (KHW03_13105) 2618179..2619048 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KHW03_RS13150 (KHW03_13110) 2619052..2619426 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KHW03_RS13155 (KHW03_13115) 2619539..2619769 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KHW03_RS13160 (KHW03_13120) 2619848..2620507 + 660 WP_002911407.1 exodeoxyribonuclease X -
KHW03_RS13165 (KHW03_13125) 2620511..2622571 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T202385 NZ_CP074558:c2617665-2617563 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT202385 NZ_CP074558:2617556-2617701 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References