Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2081206..2081244 Replicon chromosome
Accession NZ_CP074545
Organism Klebsiella aerogenes strain S33_CRE34

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2081206..2081236 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2081206..2081244 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHW00_RS10020 (KHW00_10030) 2077261..2079528 + 2268 WP_050595190.1 right-handed parallel beta-helix repeat-containing protein -
KHW00_RS10025 (KHW00_10035) 2079528..2080961 + 1434 WP_032716195.1 hypothetical protein -
- 2081206..2081236 + 31 - - Toxin
- 2081206..2081244 - 39 - - Antitoxin
KHW00_RS10030 (KHW00_10040) 2081364..2082317 - 954 WP_072207417.1 spore coat U domain-containing protein -
KHW00_RS10035 (KHW00_10045) 2082330..2084654 - 2325 WP_032705949.1 fimbria/pilus outer membrane usher protein -
KHW00_RS10040 (KHW00_10050) 2084657..2085406 - 750 WP_015366013.1 molecular chaperone -
KHW00_RS10045 (KHW00_10055) 2085424..2085942 - 519 WP_015366014.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2033297..2104078 70781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 31 bp

>T202349 NZ_CP074545:2081206-2081236 [Klebsiella aerogenes]
CGAATACAGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 39 bp

>AT202349 NZ_CP074545:c2081244-2081206 [Klebsiella aerogenes]
TAATAGATAAAAAGAGACCGAACACGATTCCTGTATTCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References