Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2038188..2038326 | Replicon | chromosome |
| Accession | NZ_CP074545 | ||
| Organism | Klebsiella aerogenes strain S33_CRE34 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2038223..2038326 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2038188..2038326 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KHW00_RS09700 (KHW00_09700) | 2033297..2035357 | + | 2061 | WP_032705952.1 | oligopeptidase B | - |
| KHW00_RS09705 (KHW00_09705) | 2035360..2036019 | - | 660 | WP_015366006.1 | exodeoxyribonuclease X | - |
| KHW00_RS09710 (KHW00_09710) | 2036099..2036329 | - | 231 | WP_015366007.1 | DNA polymerase III subunit theta | - |
| KHW00_RS09715 (KHW00_09715) | 2036464..2036838 | + | 375 | WP_015366008.1 | CopC domain-containing protein YobA | - |
| KHW00_RS09720 (KHW00_09720) | 2036842..2037711 | + | 870 | WP_032705951.1 | copper homeostasis membrane protein CopD | - |
| KHW00_RS09725 (KHW00_09725) | 2037725..2038066 | + | 342 | WP_015366010.1 | YebY family protein | - |
| - | 2038188..2038326 | - | 139 | - | - | Antitoxin |
| - | 2038223..2038326 | + | 104 | - | - | Toxin |
| KHW00_RS09730 (KHW00_09730) | 2038458..2039537 | - | 1080 | WP_032708609.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| KHW00_RS09735 (KHW00_09735) | 2039512..2039784 | - | 273 | WP_071609883.1 | excisionase | - |
| KHW00_RS09740 (KHW00_09740) | 2039851..2040243 | - | 393 | WP_125961766.1 | hypothetical protein | - |
| KHW00_RS09745 (KHW00_09745) | 2040273..2040776 | - | 504 | WP_032716233.1 | siphovirus Gp157 family protein | - |
| KHW00_RS09750 (KHW00_09750) | 2040773..2043109 | - | 2337 | WP_032716232.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2033297..2104078 | 70781 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T202341 NZ_CP074545:2038223-2038326 [Klebsiella aerogenes]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 139 bp
>AT202341 NZ_CP074545:c2038326-2038188 [Klebsiella aerogenes]
AAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTGACTGTGACAGGTTTTCCAGT
AAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTGACTGTGACAGGTTTTCCAGT
