Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2129841..2129986 Replicon chromosome
Accession NZ_CP074539
Organism Klebsiella pneumoniae strain S20_CRE20

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2129877..2129979 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2129841..2129986 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHV98_RS10290 (KHV98_10280) 2124971..2127031 + 2061 WP_004151449.1 oligopeptidase B -
KHV98_RS10295 (KHV98_10285) 2127035..2127694 - 660 WP_002911407.1 exodeoxyribonuclease X -
KHV98_RS10300 (KHV98_10290) 2127773..2128003 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KHV98_RS10305 (KHV98_10295) 2128116..2128490 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KHV98_RS10310 (KHV98_10300) 2128494..2129363 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KHV98_RS10315 (KHV98_10305) 2129380..2129718 + 339 WP_002911404.1 YebY family protein -
- 2129841..2129986 - 146 - - Antitoxin
- 2129877..2129979 + 103 - - Toxin
KHV98_RS10320 (KHV98_10310) 2130354..2130497 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KHV98_RS10325 (KHV98_10315) 2130602..2131570 - 969 WP_004151446.1 VirK/YbjX family protein -
KHV98_RS10330 (KHV98_10320) 2131727..2132380 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
KHV98_RS10335 (KHV98_10325) 2132377..2132568 - 192 WP_002911395.1 YebW family protein -
KHV98_RS10340 (KHV98_10330) 2132666..2132905 - 240 WP_002911393.1 YebV family protein -
KHV98_RS10345 (KHV98_10335) 2133021..2134454 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T202303 NZ_CP074539:2129877-2129979 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT202303 NZ_CP074539:c2129986-2129841 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References