Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2136033..2136178 Replicon chromosome
Accession NZ_CP074535
Organism Klebsiella pneumoniae strain S16_CRE16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2136069..2136171 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2136033..2136178 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHV97_RS10295 (KHV97_10290) 2131163..2133223 + 2061 WP_004151449.1 oligopeptidase B -
KHV97_RS10300 (KHV97_10295) 2133227..2133886 - 660 WP_002911407.1 exodeoxyribonuclease X -
KHV97_RS10305 (KHV97_10300) 2133965..2134195 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KHV97_RS10310 (KHV97_10305) 2134308..2134682 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KHV97_RS10315 (KHV97_10310) 2134686..2135555 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KHV97_RS10320 (KHV97_10315) 2135572..2135910 + 339 WP_002911404.1 YebY family protein -
KHV97_RS10325 (KHV97_10320) 2136546..2136689 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KHV97_RS10330 (KHV97_10325) 2136794..2137762 - 969 WP_004151446.1 VirK/YbjX family protein -
KHV97_RS10335 (KHV97_10330) 2137919..2138572 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
KHV97_RS10340 (KHV97_10335) 2138569..2138760 - 192 WP_002911395.1 YebW family protein -
KHV97_RS10345 (KHV97_10340) 2138858..2139097 - 240 WP_002911393.1 YebV family protein -
KHV97_RS10350 (KHV97_10345) 2139213..2140646 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T202283 NZ_CP074535:2136069-2136171 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT202283 NZ_CP074535:c2136178-2136033 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References