Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2010275..2010420 Replicon chromosome
Accession NZ_CP074528
Organism Klebsiella pneumoniae strain S14_CRE14

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2010311..2010413 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2010275..2010420 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHV96_RS09770 2005405..2007465 + 2061 WP_004151449.1 oligopeptidase B -
KHV96_RS09775 2007469..2008128 - 660 WP_020324964.1 exodeoxyribonuclease X -
KHV96_RS09780 2008207..2008437 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KHV96_RS09785 2008550..2008924 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KHV96_RS09790 2008928..2009797 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KHV96_RS09795 2009814..2010152 + 339 WP_002911404.1 YebY family protein -
- 2010275..2010420 - 146 - - Antitoxin
- 2010311..2010413 + 103 - - Toxin
KHV96_RS09800 2010789..2010932 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KHV96_RS09805 2011037..2012005 - 969 WP_004151446.1 VirK/YbjX family protein -
KHV96_RS09810 2012162..2012815 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KHV96_RS09815 2012812..2013003 - 192 WP_002911395.1 YebW family protein -
KHV96_RS09820 2013101..2013340 - 240 WP_002911393.1 YebV family protein -
KHV96_RS09825 2013456..2014889 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T202260 NZ_CP074528:2010311-2010413 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT202260 NZ_CP074528:c2010420-2010275 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References