Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1850562..1850707 Replicon chromosome
Accession NZ_CP074519
Organism Klebsiella pneumoniae strain S10_CRE10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1850598..1850700 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1850562..1850707 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHV94_RS09040 1845692..1847752 + 2061 WP_004151449.1 oligopeptidase B -
KHV94_RS09045 1847756..1848415 - 660 WP_002911407.1 exodeoxyribonuclease X -
KHV94_RS09050 1848494..1848724 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KHV94_RS09055 1848837..1849211 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KHV94_RS09060 1849215..1850084 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KHV94_RS09065 1850101..1850439 + 339 WP_002911404.1 YebY family protein -
- 1850562..1850707 - 146 - - Antitoxin
- 1850598..1850700 + 103 - - Toxin
KHV94_RS09070 1851075..1851218 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KHV94_RS09075 1851323..1852291 - 969 WP_074195444.1 VirK/YbjX family protein -
KHV94_RS09080 1852448..1853101 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KHV94_RS09085 1853098..1853289 - 192 WP_002911395.1 YebW family protein -
KHV94_RS09090 1853387..1853626 - 240 WP_002911393.1 YebV family protein -
KHV94_RS09095 1853742..1855175 - 1434 WP_064190786.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T202220 NZ_CP074519:1850598-1850700 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT202220 NZ_CP074519:c1850707-1850562 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References