Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3494784..3494952 Replicon chromosome
Accession NZ_CP074449
Organism Klebsiella michiganensis strain S4_CRE4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3494791..3494894 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3494784..3494952 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHV91_RS16250 (KHV91_16225) 3490058..3490576 + 519 WP_004852079.1 spore coat U domain-containing protein -
KHV91_RS16255 (KHV91_16230) 3490595..3491359 + 765 WP_049082702.1 fimbria/pilus periplasmic chaperone -
KHV91_RS16260 (KHV91_16235) 3491362..3493692 + 2331 WP_064405637.1 fimbria/pilus outer membrane usher protein -
KHV91_RS16265 (KHV91_16240) 3493707..3494666 + 960 WP_042945476.1 spore coat protein U domain-containing protein -
- 3494784..3494952 + 169 - - Antitoxin
- 3494791..3494894 - 104 - - Toxin
KHV91_RS16270 (KHV91_16245) 3495051..3495389 - 339 WP_004103344.1 YebY family protein -
KHV91_RS16275 (KHV91_16250) 3495406..3496275 - 870 WP_014229837.1 copper homeostasis membrane protein CopD -
KHV91_RS16280 (KHV91_16255) 3496280..3496654 - 375 WP_014229838.1 CopC domain-containing protein YobA -
KHV91_RS16285 (KHV91_16260) 3496790..3497020 + 231 WP_004103351.1 DNA polymerase III subunit theta -
KHV91_RS16290 (KHV91_16265) 3497099..3497758 + 660 WP_014229839.1 exodeoxyribonuclease X -
KHV91_RS16295 (KHV91_16270) 3497765..3499825 - 2061 WP_033836507.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T202206 NZ_CP074449:c3494894-3494791 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT202206 NZ_CP074449:3494784-3494952 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References