Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) KacT-ataR/DUF1778(antitoxin)
Location 2086425..2087222 Replicon chromosome
Accession NZ_CP074448
Organism Enterobacter asburiae strain S3_CRE3

Toxin (Protein)


Gene name KacT Uniprot ID -
Locus tag KHV90_RS09885 Protein ID WP_172620298.1
Coordinates 2086425..2086925 (-) Length 167 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag KHV90_RS09890 Protein ID WP_023311079.1
Coordinates 2086953..2087222 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHV90_RS09855 (KHV90_09825) 2082008..2082697 + 690 WP_033145167.1 pyrimidine utilization protein B -
KHV90_RS09860 (KHV90_09830) 2082709..2083095 + 387 WP_010429508.1 pyrimidine utilization protein C -
KHV90_RS09865 (KHV90_09835) 2083103..2083903 + 801 WP_048979076.1 pyrimidine utilization protein D -
KHV90_RS09870 (KHV90_09840) 2083913..2084503 + 591 WP_033145164.1 malonic semialdehyde reductase -
KHV90_RS09875 (KHV90_09845) 2084513..2085007 + 495 WP_048979075.1 pyrimidine utilization flavin reductase protein F -
KHV90_RS09880 (KHV90_09850) 2085029..2086351 + 1323 WP_048979074.1 pyrimidine utilization transport protein G -
KHV90_RS09885 (KHV90_09855) 2086425..2086925 - 501 WP_172620298.1 GNAT family N-acetyltransferase Toxin
KHV90_RS09890 (KHV90_09860) 2086953..2087222 - 270 WP_023311079.1 DUF1778 domain-containing protein Antitoxin
KHV90_RS09895 (KHV90_09865) 2087284..2088201 - 918 WP_048979072.1 DMT family transporter -
KHV90_RS09900 (KHV90_09870) 2088319..2088489 - 171 WP_023311077.1 general stress protein -
KHV90_RS09905 (KHV90_09875) 2088880..2089476 + 597 WP_023311076.1 NAD(P)H:quinone oxidoreductase -
KHV90_RS09910 (KHV90_09880) 2089497..2089724 + 228 WP_008499832.1 YccJ family protein -
KHV90_RS09915 (KHV90_09885) 2089758..2090999 - 1242 WP_048979071.1 bifunctional glucose-1-phosphatase/inositol phosphatase -
KHV90_RS09920 (KHV90_09890) 2091152..2091595 + 444 WP_032658095.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(2-88)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 19018.74 Da        Isoelectric Point: 7.9108

>T202196 WP_172620298.1 NZ_CP074448:c2086925-2086425 [Enterobacter asburiae]
MLSEGTDYDFEYFDCGEPSLNAFLAEHLVRQHNGRILRAYLLKERDRPRVLGYYTLSGSCFERAMLPSKTQQRRIPYINV
PSVTLGRLAVDKTLQGNEWGTTLVAHAMRVVYLASQAVGVHGIFVDALDERAKRFYLKQGFIPLTAENSHSLFFPTKSIE
RLFEQE

Download         Length: 501 bp

>T202196 NZ_CP099339:63446-63598 [Escherichia fergusonii]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10249.72 Da        Isoelectric Point: 5.8836

>AT202196 WP_023311079.1 NZ_CP074448:c2087222-2086953 [Enterobacter asburiae]
MPALKKQRIDLRLTDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWTAVMDAIDNPPEPNERLKR
AAKRLRNME

Download         Length: 270 bp

>AT202196 NZ_CP099339:c63391-63334 [Escherichia fergusonii]
GCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References