Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2147636..2147781 Replicon chromosome
Accession NZ_CP074442
Organism Klebsiella pneumoniae strain S1_CRE1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2147672..2147774 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2147636..2147781 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHV88_RS10605 (KHV88_10580) 2142766..2144826 + 2061 WP_032422099.1 oligopeptidase B -
KHV88_RS10610 (KHV88_10585) 2144830..2145489 - 660 WP_002911407.1 exodeoxyribonuclease X -
KHV88_RS10615 (KHV88_10590) 2145568..2145798 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KHV88_RS10620 (KHV88_10595) 2145911..2146285 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KHV88_RS10625 (KHV88_10600) 2146289..2147158 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KHV88_RS10630 (KHV88_10605) 2147175..2147513 + 339 WP_002911404.1 YebY family protein -
- 2147636..2147781 - 146 - - Antitoxin
- 2147672..2147774 + 103 - - Toxin
KHV88_RS10635 (KHV88_10610) 2148149..2148292 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KHV88_RS10640 (KHV88_10615) 2148397..2149365 - 969 WP_004151446.1 VirK/YbjX family protein -
KHV88_RS10645 (KHV88_10620) 2149522..2150175 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
KHV88_RS10650 (KHV88_10625) 2150172..2150363 - 192 WP_002911395.1 YebW family protein -
KHV88_RS10655 (KHV88_10630) 2150461..2150700 - 240 WP_002911393.1 YebV family protein -
KHV88_RS10660 (KHV88_10635) 2150816..2152249 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T202156 NZ_CP074442:2147672-2147774 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT202156 NZ_CP074442:c2147781-2147636 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References