Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 5990084..5990657 Replicon chromosome
Accession NZ_CP074412
Organism Pseudomonas viridiflava strain U625

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KHW14_RS26465 Protein ID WP_025993262.1
Coordinates 5990370..5990657 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KHW14_RS26460 Protein ID WP_043303383.1
Coordinates 5990084..5990383 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHW14_RS26440 (KHW14_26440) 5985863..5986186 - 324 WP_058430394.1 helix-turn-helix domain-containing protein -
KHW14_RS26445 (KHW14_26445) 5986488..5987483 - 996 WP_277302688.1 MsnO8 family LLM class oxidoreductase -
KHW14_RS26450 (KHW14_26450) 5987808..5988326 + 519 WP_122522433.1 Bro-N domain-containing protein -
KHW14_RS26455 (KHW14_26455) 5988512..5990005 + 1494 WP_057410613.1 YifB family Mg chelatase-like AAA ATPase -
KHW14_RS26460 (KHW14_26460) 5990084..5990383 + 300 WP_043303383.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
KHW14_RS26465 (KHW14_26465) 5990370..5990657 + 288 WP_025993262.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KHW14_RS26470 (KHW14_26470) 5990721..5992697 - 1977 WP_122415290.1 methyl-accepting chemotaxis protein -
KHW14_RS26475 (KHW14_26475) 5992879..5993799 - 921 WP_004887422.1 LysR substrate-binding domain-containing protein -
KHW14_RS26480 (KHW14_26480) 5993956..5995338 + 1383 WP_025993265.1 NorM family multidrug efflux MATE transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-51)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11021.52 Da        Isoelectric Point: 5.1312

>T202065 WP_025993262.1 NZ_CP074412:5990370-5990657 [Pseudomonas viridiflava]
VTTVEWSSWARQDLLAIIDYISDDNVTAAQEMKDTIESRVADLPLHPRLYKEGREPGTREMVVHPNYIVIYSERTTTLIV
LRVLHVARKWPSETE

Download         Length: 288 bp

>T202065 NZ_CP099304:c5268980-5268603 [Klebsiella michiganensis]
ATGCAAACCCAACCGCTATCCTCCACGCAGGAGGCTTCGCCACGCCCGTCACAGGTGGATATCTGGCAGCAGCTTCTGAG
TCACCTGCTGGATCGTCACTACGGTCTGACGCTTAACGACACGCCATTTGGTCACGATGGCGTGATTCAGGAGCATATCG
ACGCGGGTATCTCACTGTGCGATGCCGTGAATGTTATCGTGGAAAAGTACGATCTGGTGCGCACCGATCGTCCCGGTTTC
AGCGCAGAAACACAGTCGCCGCTTATCAGCAGTATCGATATTCTCCGCGCCCGCAAAGCCACCGGGCTGATGACCCGCAA
TGACTACAGAACGGTGACCGACATCACCACCGGTAAATACCGTGAGGTGCAGCCATGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11192.69 Da        Isoelectric Point: 6.2266

>AT202065 WP_043303383.1 NZ_CP074412:5990084-5990383 [Pseudomonas viridiflava]
MATHTSMLHVRIDNDLKTQATETLAKFGLTVSDAVRILLTRVAREGALPVGFTSDAEAYDKWFRAKVKEAMDDTQPSITH
EQMMAEAQQLIDRKRRDDS

Download         Length: 300 bp

>AT202065 NZ_CP099304:c5269391-5269032 [Klebsiella michiganensis]
TTGTCGAATGAGATACCGGCAGTAAACCACGATATCGCTGAACCCTGGTGGGGCCTTAAGCCCACCGTCACACCGTGCTT
TGGCGCACGACTGGTGCAGGAGGGCAACCAGGTGCACTATCTCGCCGACCGCGCCAGCATCACCGGTCAGTTCAGCGAGG
CGGATTTACGCCATCTTGACCAGGCCTTTCCGGTACTACTCAAACAGCTGGAATTGATGCTGGTTTCCGGTGAACTCAAT
CCTCACCATCAGCACGGCGTTACGCTCTACGCAAAAGGGTTGACCTGCGAAGCCGATTCACTCGGCTCGCATGGCTACAT
TTATATTGCGATTTATCCAACGCCTGCAGCAACCGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References