Detailed information of TA system TA202065

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 5990084..5990657
• Replicon: chromosome
• Accession: NZ_CP074412
• Organism: Pseudomonas viridiflava strain U625

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KHW14_RS26465
• Protein ID: WP_025993262.1
• Coordinates: 5990370..5990657 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: KHW14_RS26460
• Protein ID: WP_043303383.1
• Coordinates: 5990084..5990383 (+)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KHW14_RS26440 (KHW14_26440)	5985863..5986186	-	324	WP_058430394.1	helix-turn-helix domain-containing protein	-
KHW14_RS26445 (KHW14_26445)	5986488..5987483	-	996	WP_277302688.1	MsnO8 family LLM class oxidoreductase	-
KHW14_RS26450 (KHW14_26450)	5987808..5988326	+	519	WP_122522433.1	Bro-N domain-containing protein	-
KHW14_RS26455 (KHW14_26455)	5988512..5990005	+	1494	WP_057410613.1	YifB family Mg chelatase-like AAA ATPase	-
KHW14_RS26460 (KHW14_26460)	5990084..5990383	+	300	WP_043303383.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
KHW14_RS26465 (KHW14_26465)	5990370..5990657	+	288	WP_025993262.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KHW14_RS26470 (KHW14_26470)	5990721..5992697	-	1977	WP_122415290.1	methyl-accepting chemotaxis protein	-
KHW14_RS26475 (KHW14_26475)	5992879..5993799	-	921	WP_004887422.1	LysR substrate-binding domain-containing protein	-
KHW14_RS26480 (KHW14_26480)	5993956..5995338	+	1383	WP_025993265.1	NorM family multidrug efflux MATE transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-51)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11021.52 Da
• Isoelectric Point: 5.1312

>T202065 WP_025993262.1 NZ_CP074412:5990370-5990657 [Pseudomonas viridiflava]
VTTVEWSSWARQDLLAIIDYISDDNVTAAQEMKDTIESRVADLPLHPRLYKEGREPGTREMVVHPNYIVIYSERTTTLIV
LRVLHVARKWPSETE

Nucleotide

• Length: 288 bp

>T202065 NZ_CP099304:c5268980-5268603 [Klebsiella michiganensis]
ATGCAAACCCAACCGCTATCCTCCACGCAGGAGGCTTCGCCACGCCCGTCACAGGTGGATATCTGGCAGCAGCTTCTGAG
TCACCTGCTGGATCGTCACTACGGTCTGACGCTTAACGACACGCCATTTGGTCACGATGGCGTGATTCAGGAGCATATCG
ACGCGGGTATCTCACTGTGCGATGCCGTGAATGTTATCGTGGAAAAGTACGATCTGGTGCGCACCGATCGTCCCGGTTTC
AGCGCAGAAACACAGTCGCCGCTTATCAGCAGTATCGATATTCTCCGCGCCCGCAAAGCCACCGGGCTGATGACCCGCAA
TGACTACAGAACGGTGACCGACATCACCACCGGTAAATACCGTGAGGTGCAGCCATGA

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 11192.69 Da
• Isoelectric Point: 6.2266

>AT202065 WP_043303383.1 NZ_CP074412:5990084-5990383 [Pseudomonas viridiflava]
MATHTSMLHVRIDNDLKTQATETLAKFGLTVSDAVRILLTRVAREGALPVGFTSDAEAYDKWFRAKVKEAMDDTQPSITH
EQMMAEAQQLIDRKRRDDS

Nucleotide

• Length: 300 bp

>AT202065 NZ_CP099304:c5269391-5269032 [Klebsiella michiganensis]
TTGTCGAATGAGATACCGGCAGTAAACCACGATATCGCTGAACCCTGGTGGGGCCTTAAGCCCACCGTCACACCGTGCTT
TGGCGCACGACTGGTGCAGGAGGGCAACCAGGTGCACTATCTCGCCGACCGCGCCAGCATCACCGGTCAGTTCAGCGAGG
CGGATTTACGCCATCTTGACCAGGCCTTTCCGGTACTACTCAAACAGCTGGAATTGATGCTGGTTTCCGGTGAACTCAAT
CCTCACCATCAGCACGGCGTTACGCTCTACGCAAAAGGGTTGACCTGCGAAGCCGATTCACTCGGCTCGCATGGCTACAT
TTATATTGCGATTTATCCAACGCCTGCAGCAACCGCGTAA