Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YoeB-YefM |
| Location | 3499179..3499684 | Replicon | chromosome |
| Accession | NZ_CP074365 | ||
| Organism | Xanthomonas translucens strain CFBP 8304 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | KCU57_RS14995 | Protein ID | WP_237649424.1 |
| Coordinates | 3499427..3499684 (+) | Length | 86 a.a. |
Antitoxin (Protein)
| Gene name | relE | Uniprot ID | A0A1C3TRJ9 |
| Locus tag | KCU57_RS14990 | Protein ID | WP_003468816.1 |
| Coordinates | 3499179..3499430 (+) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KCU57_RS20075 | 3495661..3495783 | - | 123 | WP_272932555.1 | hypothetical protein | - |
| KCU57_RS14960 (KCU57_14865) | 3495860..3496664 | + | 805 | WP_237650971.1 | IS5 family transposase | - |
| KCU57_RS14965 (KCU57_14870) | 3496630..3496812 | - | 183 | WP_237649421.1 | hypothetical protein | - |
| KCU57_RS14970 | 3496932..3497081 | - | 150 | WP_230939940.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KCU57_RS14975 (KCU57_14880) | 3497251..3497694 | - | 444 | WP_237649422.1 | nuclear transport factor 2 family protein | - |
| KCU57_RS14980 (KCU57_14885) | 3497818..3498540 | + | 723 | WP_237649423.1 | helix-turn-helix transcriptional regulator | - |
| KCU57_RS14985 (KCU57_14890) | 3498537..3499070 | - | 534 | Protein_2962 | endonuclease | - |
| KCU57_RS14990 (KCU57_14895) | 3499179..3499430 | + | 252 | WP_003468816.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| KCU57_RS14995 (KCU57_14900) | 3499427..3499684 | + | 258 | WP_237649424.1 | Txe/YoeB family addiction module toxin | Toxin |
| KCU57_RS15000 (KCU57_14905) | 3499732..3500025 | + | 294 | WP_237649425.1 | hypothetical protein | - |
| KCU57_RS15005 (KCU57_14910) | 3500153..3501520 | - | 1368 | WP_237649185.1 | IS5 family transposase | - |
| KCU57_RS15010 (KCU57_14915) | 3501666..3501959 | + | 294 | WP_237649426.1 | hypothetical protein | - |
| KCU57_RS20080 | 3502101..3502226 | + | 126 | WP_272932556.1 | hypothetical protein | - |
| KCU57_RS15015 (KCU57_14920) | 3502587..3503552 | - | 966 | WP_065898826.1 | IS1595 family transposase | - |
| KCU57_RS15020 (KCU57_14925) | 3503639..3504091 | - | 453 | WP_237649427.1 | hypothetical protein | - |
| KCU57_RS15025 (KCU57_14930) | 3504280..3504600 | + | 321 | WP_237649428.1 | helix-turn-helix domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 3490344..3505073 | 14729 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 10096.60 Da Isoelectric Point: 9.6593
>T201961 WP_237649424.1 NZ_CP074365:3499427-3499684 [Xanthomonas translucens]
VTLQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQHDPFQGVGKPEPLRHALAGYWSRRINDAHRIVYKVEAGVLLIAQV
RYHYV
VTLQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQHDPFQGVGKPEPLRHALAGYWSRRINDAHRIVYKVEAGVLLIAQV
RYHYV
Download Length: 258 bp
>T201961 NZ_CP099140:c5141510-5141127 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9281.56 Da Isoelectric Point: 5.1186
>AT201961 WP_003468816.1 NZ_CP074365:3499179-3499430 [Xanthomonas translucens]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE
Download Length: 252 bp
>AT201961 NZ_CP099140:c5141752-5141510 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|