Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2413075..2413745 Replicon chromosome
Accession NZ_CP074364
Organism Xanthomonas translucens pv. cerealis strain CFBP 2541

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KHA79_RS10670 Protein ID WP_039009849.1
Coordinates 2413075..2413494 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A514EBP8
Locus tag KHA79_RS10675 Protein ID WP_039009846.1
Coordinates 2413491..2413745 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHA79_RS10650 (KHA79_10590) 2409102..2411417 + 2316 WP_080763545.1 TonB-dependent siderophore receptor -
KHA79_RS10655 (KHA79_10595) 2411533..2411952 + 420 WP_039010109.1 hypothetical protein -
KHA79_RS10660 (KHA79_10600) 2411933..2412334 + 402 WP_039009851.1 hypothetical protein -
KHA79_RS10665 (KHA79_10605) 2412538..2412918 - 381 Protein_2101 conjugal transfer protein TrbJ -
KHA79_RS10670 (KHA79_10610) 2413075..2413494 - 420 WP_039009849.1 type II toxin-antitoxin system VapC family toxin Toxin
KHA79_RS10675 (KHA79_10615) 2413491..2413745 - 255 WP_039009846.1 Arc family DNA-binding protein Antitoxin
KHA79_RS10680 (KHA79_10620) 2414157..2414438 - 282 WP_039009843.1 TraK family protein -
KHA79_RS10685 (KHA79_10625) 2415006..2415500 + 495 WP_080763544.1 hypothetical protein -
KHA79_RS10690 (KHA79_10630) 2415626..2416957 - 1332 WP_230812383.1 AvrBs1/Avra family type III secretion system effector -
KHA79_RS10695 (KHA79_10635) 2417057..2418127 - 1071 WP_176717100.1 type III secretion system effector XopH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2403043..2418127 15084


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15059.30 Da        Isoelectric Point: 5.2075

>T201955 WP_039009849.1 NZ_CP074364:c2413494-2413075 [Xanthomonas translucens pv. cerealis]
MIVLDTNVVSEAMKPEPNPAVRAWLNEQVAETLYLSSVTLAELFFGIVALPNGKRKKGLGEALDGLLELFGERVLMFDTE
AARHYAELAVKARTAGKDFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHR

Download         Length: 420 bp

>T201955 NZ_CP099140:1908153-1908255 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9608.00 Da        Isoelectric Point: 7.2078

>AT201955 WP_039009846.1 NZ_CP074364:c2413745-2413491 [Xanthomonas translucens pv. cerealis]
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSEKRIRMGDALAELGRRVRLTNDDFAVLDQVRDKVPAEP
MRFE

Download         Length: 255 bp

>AT201955 NZ_CP099140:c1908262-1908117 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A514EBP8

References