201954

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 278278..278663 Replicon chromosome
Accession NZ_CP074364
Organism Xanthomonas translucens pv. cerealis strain CFBP 2541

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KHA79_RS01205 Protein ID WP_003469322.1
Coordinates 278529..278663 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A514EHQ9
Locus tag KHA79_RS01200 Protein ID WP_039006387.1
Coordinates 278278..278430 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHA79_RS01170 (KHA79_01170) 273783..274055 - 273 WP_176717140.1 hypothetical protein -
KHA79_RS01175 (KHA79_01175) 274217..275188 + 972 WP_039006392.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KHA79_RS01180 (KHA79_01180) 275185..275925 + 741 WP_039006389.1 type III pantothenate kinase -
KHA79_RS01185 (KHA79_01185) 275935..276789 + 855 WP_068830182.1 SPOR domain-containing protein -
KHA79_RS01195 (KHA79_01195) 277210..278133 + 924 WP_039006388.1 arginase -
KHA79_RS01200 (KHA79_01200) 278278..278430 + 153 WP_039006387.1 entericidin A/B family lipoprotein Antitoxin
KHA79_RS01205 (KHA79_01205) 278529..278663 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KHA79_RS01210 (KHA79_01210) 278863..279078 + 216 WP_039006382.1 CsbD family protein -
KHA79_RS01215 (KHA79_01215) 279148..279990 - 843 WP_080763519.1 hypothetical protein -
KHA79_RS01220 (KHA79_01220) 280101..281411 + 1311 WP_039006381.1 tryptophan--tRNA ligase -
KHA79_RS01225 (KHA79_01225) 281694..282617 + 924 WP_039006379.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T201954 WP_003469322.1 NZ_CP074364:278529-278663 [Xanthomonas translucens pv. cerealis]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T201954 NZ_CP099140:789531-789941 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5363.35 Da        Isoelectric Point: 8.1210

>AT201954 WP_039006387.1 NZ_CP074364:278278-278430 [Xanthomonas translucens pv. cerealis]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVENKADDCKDGKC

Download         Length: 153 bp

>AT201954 NZ_CP099140:789284-789550 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A514EHQ9

References