Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4342925..4343310 Replicon chromosome
Accession NZ_CP074361
Organism Xanthomonas translucens pv. undulosa strain CFBP 2055

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KCU58_RS18985 Protein ID WP_003469322.1
Coordinates 4342925..4343059 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag KCU58_RS18990 Protein ID WP_003469323.1
Coordinates 4343158..4343310 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KCU58_RS18970 (KCU58_18850) 4339350..4340273 - 924 WP_003469319.1 MBL fold metallo-hydrolase -
KCU58_RS18975 (KCU58_18855) 4340350..4341750 - 1401 WP_003469320.1 tryptophan--tRNA ligase -
KCU58_RS18980 (KCU58_18860) 4341861..4342715 + 855 WP_003469321.1 hypothetical protein -
KCU58_RS18985 (KCU58_18865) 4342925..4343059 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KCU58_RS18990 (KCU58_18870) 4343158..4343310 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
KCU58_RS18995 (KCU58_18875) 4343455..4344377 - 923 Protein_3744 arginase -
KCU58_RS19005 (KCU58_18885) 4344783..4345601 - 819 WP_047325438.1 SPOR domain-containing protein -
KCU58_RS19010 (KCU58_18890) 4345611..4346351 - 741 WP_003469293.1 type III pantothenate kinase -
KCU58_RS19015 (KCU58_18895) 4346348..4347367 - 1020 WP_162489024.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KCU58_RS19020 (KCU58_18900) 4347472..4347735 + 264 WP_038238001.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T201950 WP_003469322.1 NZ_CP074361:c4343059-4342925 [Xanthomonas translucens pv. undulosa]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T201950 NZ_CP099128:4415102-4415479 [Citrobacter freundii]
GTGCAAACCCAACCACTATCCTCCACGCATGAGACCTCACCACGTCCGTCCCCCGTGGATATCTGGCAGCACCTCCTGAA
CCATCTGCTGGATCGTCACTACGGTCTGACGCTAAACGACACGCCATTTGGCAACGATGGCGTGATCCAGGAGCATATCG
ACGCCGGTATCTCACTGTGCGACGCGGTGAACTTTATCGTGGAAAAGTACGACCTGGTCCGTACTGACAGACGCGGCTTT
AGCGCAGACACACAGTCACCGCTTATCGGCAGTATTGATATCCTCCGAGCCCGGAAGGCGACCGGGCTGATGACCCGTCA
TGGCTACAGACCTGTGACAGATCTCATTACCGGCAAATACAAAAAGGAACAACAATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT201950 WP_003469323.1 NZ_CP074361:c4343310-4343158 [Xanthomonas translucens pv. undulosa]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT201950 NZ_CP099128:4414691-4415050 [Citrobacter freundii]
TTGTCGAATAAAATACCGGCAGAAAACCACGATATCACTGAACCCTGGTGGGGGCTTAAACGCAGTATCACGCCCTGTTT
TGGTGCCCGTCTGGTGCAGGAGGGCAACCGGCTGCACTATCTCGCCGACCGCGCGAGTATCGCCGGCACGTTCAGCGACG
CGGATTTACGCCATCTTGACCAGGCGTTTCCGGTACAGCTCAAACAGCTTGAGCTGATGCTGGTTTCCGGTGAACTCAAT
CCCCGCCATCAGCACTGCGTCACATTATACTCAAAAGGGCTGACCTGCGAGGCCGACAGCCTCGGCTCGCATGGATACGT
GTACATCGCGATTTACCCGACACCTGCAGCAACCGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References