Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3618163..3618668 Replicon chromosome
Accession NZ_CP074361
Organism Xanthomonas translucens pv. undulosa strain CFBP 2055

Toxin (Protein)


Gene name relE Uniprot ID A0A2S0NY60
Locus tag KCU58_RS15580 Protein ID WP_003468814.1
Coordinates 3618411..3618668 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag KCU58_RS15575 Protein ID WP_003468816.1
Coordinates 3618163..3618414 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KCU58_RS15545 (KCU58_15435) 3614025..3614315 - 291 WP_003468827.1 hypothetical protein -
KCU58_RS15550 (KCU58_15440) 3614650..3614925 + 276 WP_003468826.1 hypothetical protein -
KCU58_RS15555 (KCU58_15445) 3615093..3615947 - 855 WP_196479394.1 hypothetical protein -
KCU58_RS15560 (KCU58_15450) 3615951..3616400 - 450 WP_003468823.1 nuclear transport factor 2 family protein -
KCU58_RS15565 (KCU58_15455) 3616524..3617246 + 723 WP_003468821.1 helix-turn-helix transcriptional regulator -
KCU58_RS15570 (KCU58_15460) 3617243..3618007 - 765 WP_003468819.1 DNA-formamidopyrimidine glycosylase family protein -
KCU58_RS15575 (KCU58_15465) 3618163..3618414 + 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KCU58_RS15580 (KCU58_15470) 3618411..3618668 + 258 WP_003468814.1 Txe/YoeB family addiction module toxin Toxin
KCU58_RS15590 (KCU58_15480) 3618961..3619314 - 354 WP_003468813.1 PilZ domain-containing protein -
KCU58_RS15595 (KCU58_15485) 3619311..3620288 - 978 WP_003468812.1 DNA polymerase III subunit delta' -
KCU58_RS15600 (KCU58_15490) 3620285..3620953 - 669 WP_003468811.1 dTMP kinase -
KCU58_RS15605 (KCU58_15495) 3620950..3622017 - 1068 WP_170873989.1 endolytic transglycosylase MltG -
KCU58_RS15610 (KCU58_15500) 3622087..3623436 - 1350 WP_003468809.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10173.68 Da        Isoelectric Point: 9.6587

>T201949 WP_003468814.1 NZ_CP074361:3618411-3618668 [Xanthomonas translucens pv. undulosa]
VTLQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYV

Download         Length: 258 bp

>T201949 NZ_CP099128:c4238587-4238303 [Citrobacter freundii]
ATGACTTATGAACTGGAATTCGACCCGAGAGCCTTAAAAGAGTGGCATAAACTGGGTGATACGGTGAAGGCTCAGTTTAA
GAAGAAGTTGGCCGACGTGTTGTTGAACCCCAGAATTGACTCTGCCCGTTTAAACGGTCTTCCAGATTGCTATAAAATTA
AGCTTAAATCGTCCGGCTATCGTCTGGTGTACCAGGTTCGGGATGAGGTTGTGACCGTGTTTGTTGTCGCGGTCGGCAAG
CGAGAGCATTCGGCCGTTTATCTCGATGCAAACAAACGGCTTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT201949 WP_003468816.1 NZ_CP074361:3618163-3618414 [Xanthomonas translucens pv. undulosa]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT201949 NZ_CP099128:c4238819-4238577 [Citrobacter freundii]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCTGTGCGATTACTGTTTCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACCGTTAGCGACA
GCGAAGATACACTGATTCAGACAGTCCGGGAGAGGCTGGCCAGCCCGCAAAAAGGAATCAAGGTTAGTCTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S0NY60

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References