Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 2635407..2636077 | Replicon | chromosome |
| Accession | NZ_CP074361 | ||
| Organism | Xanthomonas translucens pv. undulosa strain CFBP 2055 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | KCU58_RS11430 | Protein ID | WP_003473425.1 |
| Coordinates | 2635407..2635826 (-) | Length | 140 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | A0A2S7EM03 |
| Locus tag | KCU58_RS11435 | Protein ID | WP_003473422.1 |
| Coordinates | 2635823..2636077 (-) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KCU58_RS11390 (KCU58_11290) | 2630629..2630997 | - | 369 | WP_003466572.1 | conjugal transfer transcriptional regulator TraJ | - |
| KCU58_RS11395 (KCU58_11295) | 2631000..2631284 | - | 285 | WP_003466574.1 | hypothetical protein | - |
| KCU58_RS11400 (KCU58_11300) | 2631296..2631538 | - | 243 | WP_003466577.1 | type I toxin-antitoxin system ptaRNA1 family toxin | - |
| KCU58_RS11405 (KCU58_11305) | 2631652..2633052 | - | 1401 | WP_003466580.1 | P-type conjugative transfer protein TrbL | - |
| KCU58_RS11410 (KCU58_11310) | 2633054..2633212 | - | 159 | WP_155522240.1 | hypothetical protein | - |
| KCU58_RS11415 (KCU58_11315) | 2633223..2633918 | - | 696 | Protein_2256 | P-type conjugative transfer protein TrbJ | - |
| KCU58_RS11420 (KCU58_11320) | 2634026..2634319 | + | 294 | WP_038237253.1 | transposase | - |
| KCU58_RS11425 (KCU58_11325) | 2634316..2635176 | + | 861 | WP_060748765.1 | IS3 family transposase | - |
| KCU58_RS11430 (KCU58_11330) | 2635407..2635826 | - | 420 | WP_003473425.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| KCU58_RS11435 (KCU58_11335) | 2635823..2636077 | - | 255 | WP_003473422.1 | hypothetical protein | Antitoxin |
| KCU58_RS11440 (KCU58_11340) | 2636489..2636770 | - | 282 | WP_003473419.1 | TraK family protein | - |
| KCU58_RS11445 (KCU58_11345) | 2637416..2638458 | + | 1043 | WP_230938149.1 | IS3 family transposase | - |
| KCU58_RS11450 (KCU58_11350) | 2638576..2639057 | + | 482 | Protein_2263 | IS3 family transposase | - |
| KCU58_RS11455 (KCU58_11355) | 2639103..2639858 | + | 756 | Protein_2264 | IS3 family transposase | - |
| KCU58_RS11460 (KCU58_11360) | 2639837..2640805 | - | 969 | WP_058197552.1 | IS5 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 2634949..2639641 | 4692 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 14944.21 Da Isoelectric Point: 5.2082
>T201948 WP_003473425.1 NZ_CP074361:c2635826-2635407 [Xanthomonas translucens pv. undulosa]
MIVLDTNVVSEAMKPEPNPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFSERVLMFDTE
AARNYAELAVKARIAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHR
MIVLDTNVVSEAMKPEPNPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFSERVLMFDTE
AARNYAELAVKARIAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHR
Download Length: 420 bp
>T201948 NZ_CP099128:3590912-3591130 [Citrobacter freundii]
ATGTCCGATAAACCATTAACTAAAACAGATTATTTGATGCGCCTGCGACGTTGCCAGACAATTGATACGCTAGAGCGCGT
TATTGAAAAAAATAAATATGAATTGTCCGACAACGAACTGGCTGTATTTTACTCAGCAGCAGATCATCGCCTTGCTGAAT
TGACCATGAATAAGCTTTACGACAAGATTCCAACTTCTGTTTGGAAATTCATTCGCTAA
ATGTCCGATAAACCATTAACTAAAACAGATTATTTGATGCGCCTGCGACGTTGCCAGACAATTGATACGCTAGAGCGCGT
TATTGAAAAAAATAAATATGAATTGTCCGACAACGAACTGGCTGTATTTTACTCAGCAGCAGATCATCGCCTTGCTGAAT
TGACCATGAATAAGCTTTACGACAAGATTCCAACTTCTGTTTGGAAATTCATTCGCTAA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9507.88 Da Isoelectric Point: 7.2071
>AT201948 WP_003473422.1 NZ_CP074361:c2636077-2635823 [Xanthomonas translucens pv. undulosa]
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSQKRIRMGDALAELGRRVGLTNDDFAVLDQVRDKVPAEP
MRFE
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSQKRIRMGDALAELGRRVGLTNDDFAVLDQVRDKVPAEP
MRFE
Download Length: 255 bp
>AT201948 NZ_CP099128:3590510-3590884 [Citrobacter freundii]
ATGGATGAATACTCACCCAAAAGACATGATATCGCGCAGCTTAAATTTCTCTGCGAAACTCTGTATCATGACTGTCTTGC
AAACCTTGAACAAAGTAACCATGGCTGGGTTAATGACCCTACCTCTGCAACCAGCTTGCAGCTCAATGAACTGATAGAGC
ATATTGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAGGACAATAAGCTGATCGCGCAGATAGATGAATACCTG
GATGACACTTTTATGTTGTTCAGCAGTTATGGTATTAATACGCAGGATCTGCAGAAATGGCGGAAGTCAGGTAATCGACT
GTTTCGCTGTTTTGTCAATGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA
ATGGATGAATACTCACCCAAAAGACATGATATCGCGCAGCTTAAATTTCTCTGCGAAACTCTGTATCATGACTGTCTTGC
AAACCTTGAACAAAGTAACCATGGCTGGGTTAATGACCCTACCTCTGCAACCAGCTTGCAGCTCAATGAACTGATAGAGC
ATATTGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAGGACAATAAGCTGATCGCGCAGATAGATGAATACCTG
GATGACACTTTTATGTTGTTCAGCAGTTATGGTATTAATACGCAGGATCTGCAGAAATGGCGGAAGTCAGGTAATCGACT
GTTTCGCTGTTTTGTCAATGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|