Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 3653559..3654359 Replicon chromosome
Accession NZ_CP074352
Organism Siccibacter colletis strain YSD YN2

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag KFZ77_RS17520 Protein ID WP_264384919.1
Coordinates 3653832..3654359 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag KFZ77_RS17515 Protein ID WP_031521460.1
Coordinates 3653559..3653828 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFZ77_RS17495 (KFZ77_17480) 3649628..3650203 + 576 WP_031521500.1 transcriptional regulator -
KFZ77_RS17500 (KFZ77_17485) 3650283..3652325 + 2043 WP_264384918.1 DUF1176 domain-containing protein -
KFZ77_RS17510 (KFZ77_17495) 3652651..3653355 - 705 Protein_3416 ash family protein -
KFZ77_RS17515 (KFZ77_17500) 3653559..3653828 + 270 WP_031521460.1 DUF1778 domain-containing protein Antitoxin
KFZ77_RS17520 (KFZ77_17505) 3653832..3654359 + 528 WP_264384919.1 GNAT family N-acetyltransferase Toxin
KFZ77_RS17525 (KFZ77_17510) 3654541..3656166 + 1626 WP_264384920.1 phosphoethanolamine transferase EptA -
KFZ77_RS17530 (KFZ77_17515) 3656167..3656838 + 672 WP_264384921.1 two-component system response regulator PmrA -
KFZ77_RS17535 (KFZ77_17520) 3656842..3657927 + 1086 WP_264384922.1 two-component system sensor histidine kinase PmrB -
KFZ77_RS17540 (KFZ77_17525) 3658050..3658970 + 921 WP_236633838.1 nickel/cobalt transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(94-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19603.52 Da        Isoelectric Point: 8.4816

>T201868 WP_264384919.1 NZ_CP074352:3653832-3654359 [Siccibacter colletis]
MPGLKIEILAEGCCYDTTAFDCGDATLNTFLTEHLQRQHSRRVLRAYILRTTDEAARVRGFYTLSGSCFEKAQLPSRTQQ
KKMPYRNVPAVTLGRLAIDQKLQGEGWGSTLVSHAMKVVYQASLTVGIHGMFVDALNEKARRFYLSLGFIPLTGDNHQAL
FYPVTAMEALFAEHN

Download         Length: 528 bp

>T201868 NZ_CP098808:c1351380-1350973 [Ensifer adhaerens]
ATGTTGAAATACATGCTCGACACCAATATCTGCATCTACACGGTCAAGAACCGGCCGCAGCAGGTTCGTGAGGCGTTCAA
CAGGCATCACGGCCAACTGTGCATCAGCTCGGTCAGCCTGATGGAGTTGATCTACGGCGCGGAAAGATCCGCAATGCCCG
AGCGTAACCTATCGGTCATAGAGGGGTTTGCCGCGCGTCTTGAGGTTCTCAACTACGATCAGGCGGCAGCCAGCCATACC
GGACAGTTGCGCGCCGAACTCGCCCGCAGTGGCACGCCGATAGGGCCTTACGATCAGTTGATCGCGGGTCATGCACGGTC
TCAAGGCTTGATCCTCGTGACCAACAACCGGCGGGAGTTCGATCGTGTGCCCGGCTTGCGAGTCGAGGACTGGACCGCGG
CGCCCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10147.67 Da        Isoelectric Point: 7.0150

>AT201868 WP_031521460.1 NZ_CP074352:3653559-3653828 [Siccibacter colletis]
MPAQKNQRIDLRLSLEDKNMIEEAAAMTNQTMSQFMLNSASERAAEIIEQHRRIVLNDASWDQVMDAISTPPVPVAKLKR
AARRLKDLE

Download         Length: 270 bp

>AT201868 NZ_CP098808:c1351613-1351380 [Ensifer adhaerens]
ATGTCGGAACAGGGCGCAGTTTTTCTCACCAATCGTAGTCAGGCGATCCGGCTGCCGAGGGCCGTAGCGCTTCCGGAGGA
CGTCAAACGCGTCGATATCGTCGCGGTGGGGCGAACGCGCATCATTACACCCGCAGGCGAGGCCTGGGACAGTTGGTTCG
ACGGCGAGCTCGTCACAGCCGATTTCATGGTGCAGAGAGAGCAGCCGGAGGCCCAGGAACGCGAGCCACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References