Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3366633..3367296 Replicon chromosome
Accession NZ_CP074352
Organism Siccibacter colletis strain YSD YN2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag KFZ77_RS16140 Protein ID WP_031519722.1
Coordinates 3366633..3367049 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag KFZ77_RS16145 Protein ID WP_031519720.1
Coordinates 3367030..3367296 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFZ77_RS16120 (KFZ77_16100) 3362588..3364321 - 1734 WP_264384776.1 single-stranded-DNA-specific exonuclease RecJ -
KFZ77_RS16125 (KFZ77_16105) 3364325..3365035 - 711 WP_264384777.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
KFZ77_RS16130 (KFZ77_16110) 3365065..3365961 - 897 WP_031519725.1 site-specific tyrosine recombinase XerD -
KFZ77_RS16135 (KFZ77_16115) 3366062..3366583 + 522 WP_031519723.1 flavodoxin FldB -
KFZ77_RS16140 (KFZ77_16120) 3366633..3367049 - 417 WP_031519722.1 protein YgfX Toxin
KFZ77_RS16145 (KFZ77_16125) 3367030..3367296 - 267 WP_031519720.1 FAD assembly factor SdhE Antitoxin
KFZ77_RS16150 (KFZ77_16130) 3367559..3368542 + 984 WP_264384778.1 tRNA-modifying protein YgfZ -
KFZ77_RS16155 (KFZ77_16135) 3368582..3369241 - 660 WP_264384779.1 hemolysin III family protein -
KFZ77_RS16160 (KFZ77_16140) 3369553..3370281 + 729 WP_031519714.1 MurR/RpiR family transcriptional regulator -
KFZ77_RS16165 (KFZ77_16145) 3370445..3371878 + 1434 WP_264384780.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16517.49 Da        Isoelectric Point: 11.3834

>T201867 WP_031519722.1 NZ_CP074352:c3367049-3366633 [Siccibacter colletis]
VVLWHSDLRVSWRSQWLSLLLHGVVAAIVLFVPWPLSYTPVWMLLLSLVVFDCVRSQRRINARQGEVKLLMENRFKWQGA
EWEIVGEPWTIQSGMMLRLRKPGKRRCKHLWLAADSMDDREWRNLRRLILQTPTRSHY

Download         Length: 417 bp

>T201867 NZ_CP098808:1119275-1119712 [Ensifer adhaerens]
GTGAGCAACCTTTTCATGCTGGACACAAATATCGTGTTCGAGTTGGCTCGGAACCCGAGAGGGCAGGTCGCTGAACGTAT
TGCGGCGGTCGGGTCGGAGGCAATCTGCGTCAGCATCATAACGGCGGCAGAATTGCGTTATGGATGCGCCAAGAAGGGTT
CCCCGAAGCTGCTGGCCCAAATCGAAGCCCTTCTAGAAAGCATTCTGGTGCTCGCGCTCGACGTGCCCGCCGATGCCAAG
TACGGCAACATCCGCACTGAGTTGGAAGCTGCAGGCAAACCAATCGGCCCAAATGACCTATTGATCGCTGCTCATGCCTG
TGCCGCAGGAGCAGTTCTCGTCACAGCCAATGCCCGTGAGTTCACGCGCATTCCCAACCTTCGGGTTGAAAACTGGCTGG
ACGCGACCTCAAAGCAACTTAGGGGTGCCTCCAACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10473.02 Da        Isoelectric Point: 5.1496

>AT201867 WP_031519720.1 NZ_CP074352:c3367296-3367030 [Siccibacter colletis]
MDITNKARIHWACRRGMRELDISVMPFFEHEYDSLSDDDKRLFVRLLECDDPDLFNWLMNHGKPADAELERMVLLIQKRN
QERGPVAL

Download         Length: 267 bp

>AT201867 NZ_CP098808:1119012-1119278 [Ensifer adhaerens]
ATGCCGCAGATTAGACACAACGAACCTCCTGCGAGGGAAGCTAAGCTCTTCCGGAATAACAAGAGCCAGGCTGTTCGCAT
CCCGGCTGACTTTGAGCTTCCTGGCGATCGAGTGATGATCCATCGCGACGGGGATCGGCTTATAATAGAGCCGCTGCGTC
GCAAGAACCTGCTGGAAGTCTTGGCAGGTCTAGATCCTCTTGGGCCTGAAGATCAGTTCCCGGATATTGACGAGACTTTG
TTGCCCGCCAAGGAAATCGACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References