Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 981030..981651 Replicon chromosome
Accession NZ_CP074352
Organism Siccibacter colletis strain YSD YN2

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag KFZ77_RS04765 Protein ID WP_031524357.1
Coordinates 981030..981248 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag KFZ77_RS04770 Protein ID WP_264385579.1
Coordinates 981277..981651 (-) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFZ77_RS04740 (KFZ77_04740) 977172..979070 + 1899 WP_264385576.1 methyl-accepting chemotaxis protein -
KFZ77_RS04745 (KFZ77_04745) 979184..979450 + 267 WP_264385577.1 type B 50S ribosomal protein L31 -
KFZ77_RS04750 (KFZ77_04750) 979450..979590 + 141 WP_031524353.1 type B 50S ribosomal protein L36 -
KFZ77_RS04755 (KFZ77_04755) 979627..980112 - 486 WP_031524354.1 YlaC family protein -
KFZ77_RS04760 (KFZ77_04760) 980245..980796 - 552 WP_264385578.1 maltose O-acetyltransferase -
KFZ77_RS04765 (KFZ77_04765) 981030..981248 - 219 WP_031524357.1 HHA domain-containing protein Toxin
KFZ77_RS04770 (KFZ77_04770) 981277..981651 - 375 WP_264385579.1 Hha toxicity modulator TomB Antitoxin
KFZ77_RS04775 (KFZ77_04775) 982153..985302 - 3150 WP_031524359.1 multidrug efflux RND transporter permease subunit AcrB -
KFZ77_RS04780 (KFZ77_04780) 985325..986518 - 1194 WP_264385580.1 multidrug efflux RND transporter periplasmic adaptor subunit AcrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8608.06 Da        Isoelectric Point: 9.4828

>T201857 WP_031524357.1 NZ_CP074352:c981248-981030 [Siccibacter colletis]
MSTKPLTKIDYLMRLRRCQSIDTLERVIEKNKYELPDNELTVFYSAADHRLAELTMNKLYDKIPASVWKFVR

Download         Length: 219 bp

>T201857 NZ_CP098801:430978-431397 [Rhizobium anhuiense bv. trifolii]
ATGATCTTGTTGGACACCAACGTCTTATCCGAACCGTGGAAACCGGCTCCCGATGAGCGAGTGGTCGCCTGGCTAGATGC
CCAAGCCATCGAGACGCTGTTTCTTTCCGTAATGACGATTGCTGAACTTCGCTTCGGGATTGCGGCCATGCCGCTAGGGA
AGCGACAAACCATCCTTCACGATCGACTTGAGGGCGAAGTGTTGCCGCATTTTTCCGAGCGCATCCTGTCCTTCAATCTG
GCGAGTTCGCAGTTCTACTCGGAACTGATGGTGCGCGCGCGAGTCTCTGGGAGGACTATCGGCACGTCTGATGGCTACAT
TGCAGCTACAGCAGCAGCGAACGGCCTCGCGGTCGCAACTCGCGATACAAGCCCGTTCGAGGCTGCCGGGTTGAAAGTGA
TTAATCCCTGGGCCCGATAA

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 14505.33 Da        Isoelectric Point: 5.1350

>AT201857 WP_264385579.1 NZ_CP074352:c981651-981277 [Siccibacter colletis]
MDEYSPKRHDIAQLKFLCETLYHDCLANLGESHHGWVNDPTSAINLQLNELIEHIATFALNYKIKHDEDNILIEQIDEYL
DDTFMLFSNYGINAQDLQKWRKSGNRLFRCFLNVSRANPVSLSF

Download         Length: 375 bp

>AT201857 NZ_CP098801:430727-430981 [Rhizobium anhuiense bv. trifolii]
GTGCCGGCGGTCACCATTCGAAATCTTTCTGACGAAACACATCGTGCTCTGCGGGTGCGAGCGGCACATCATGGCCGCAG
CACCGAGGCCGAGATCCGTGACATTATCGAAGCCGCTGTCCGTCCCTCTGAACGCGTGAAGCTAGGTTCCTTACTGGCAG
CTATTGGCCGTGAAGCTGAGCTTTCCAATCTGGATGTCGAAGCGCTTCAGAATAATCGCGATGACACTCCTGCTGTACCG
ATGCCCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References