Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 205050..205516 Replicon chromosome
Accession NZ_CP074352
Organism Siccibacter colletis strain YSD YN2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KFZ77_RS00975 Protein ID WP_264385218.1
Coordinates 205050..205325 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KFZ77_RS00980 Protein ID WP_264385219.1
Coordinates 205325..205516 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFZ77_RS00955 (KFZ77_00960) 200621..201463 - 843 WP_031521943.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
KFZ77_RS00960 (KFZ77_00965) 201565..202041 - 477 WP_264385215.1 hypothetical protein -
KFZ77_RS00965 (KFZ77_00970) 202224..204266 + 2043 WP_264385216.1 oligopeptidase A -
KFZ77_RS00970 (KFZ77_00975) 204275..205027 + 753 WP_264385217.1 16S rRNA (guanine(1516)-N(2))-methyltransferase RsmJ -
KFZ77_RS00975 (KFZ77_00980) 205050..205325 - 276 WP_264385218.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KFZ77_RS00980 (KFZ77_00985) 205325..205516 - 192 WP_264385219.1 stability determinant Antitoxin
KFZ77_RS00985 (KFZ77_00990) 205645..206082 - 438 WP_031521937.1 universal stress protein UspA -
KFZ77_RS00990 (KFZ77_00995) 206467..206802 + 336 WP_031521936.1 universal stress protein UspB -
KFZ77_RS00995 (KFZ77_01000) 206854..208356 - 1503 WP_031521935.1 inorganic phosphate transporter PitA -
KFZ77_RS01000 (KFZ77_01005) 208587..209786 + 1200 WP_264385220.1 NAD(P)/FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10442.02 Da        Isoelectric Point: 5.5512

>T201856 WP_264385218.1 NZ_CP074352:c205325-205050 [Siccibacter colletis]
MLPIQWTEEAKTDLFTLISFIALENPYAAESLLQQIDAAILPAAEHPYMFRAGRVDGTREVIAHPNYIVVYQVRNECIRI
ISVVHSRQQYP

Download         Length: 276 bp

>T201856 NZ_CP098801:321311-321814 [Rhizobium anhuiense bv. trifolii]
GTGACTCTCAGCGCACCCATCCCACTGGCCGATCATCACGAGCTGTCAGAATTCAATTCCAGTGTCCCTGAATTGAACGA
CTGGCTGCGTCGCCGCGCCCGCGCCAATCAGGTAGGTGGCGCATCGCGCACCTTTGTCGTGTGTGAAGAAAATCGCGTCA
TCGCTTATTACGCACTCGCTTCCGGGGCCGTGAAACAGCCGGAAGCGCCAGGCCGTTTTCGGCGCAACATGCCCGATCCA
ATTCCGGTTGCCGTGCTTGGTCGTCTCGCCATTGATCAGTCCTATCAGGGGCGGGGGATCGGCAGAGCGTTGGTGCGCGA
CGCAGGCTTACGCTTGCTCAATGCCGCTGAAATCCTCGGCATACGAGGCGTGTTTGTGCATGCGATTTCCAATGATGCGC
GAGCCTTCTATCAGGCGGTCGGCTTTCTTCCTTCGCCATCTGATCCCATGATGCGGATGGTCGGGCTGAATGATTTCAGC
AGCGCGCTGAACTCCCAACCGTAG

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7189.06 Da        Isoelectric Point: 6.7235

>AT201856 WP_264385219.1 NZ_CP074352:c205516-205325 [Siccibacter colletis]
MTKNLSPLVSEFETQEQAESYDRWYREKVDAAMHSTHAVSSHDDVIGGARKIIDEIKAKRKLA

Download         Length: 192 bp

>AT201856 NZ_CP098801:321015-321314 [Rhizobium anhuiense bv. trifolii]
ATGCCCACCACCTCGCATACAAGTATAAGCCCGGACGCCAGCGTGCCGCTGAATATGCGAATCAAGCCTGCGACCCGCAA
CTTGATCGACCGCGCCGCTGAATTGCTCGGCAAGACGCGCACAGATTTCATGCTGGAGGCTTCAGAGCGTCGTGCCGAGG
AGGTGCTGCTTGACCGTACCATATTCACGGTTAGCCCCGAAATCTATGCCGAATACCTTGCCCGACTGGATGTACCCACG
CAGCCCAATGAGCGTCTGAGACGCACGATGTCCACCAAAGCGCCGTGGGATGAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References