Detailed information of TA system TA201847

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): shpAB/BrnT-BrnA
• Location: 4058423..4059005
• Replicon: chromosome
• Accession: NZ_CP074350
• Organism: Pantoea dispersa strain YSD_J2

Toxin (Protein)

• Gene name: shpA
• Uniprot ID: -
• Locus tag: KFZ74_RS19050
• Protein ID: WP_238561287.1
• Coordinates: 4058706..4059005 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: shpB
• Uniprot ID: -
• Locus tag: KFZ74_RS19045
• Protein ID: WP_238561286.1
• Coordinates: 4058423..4058725 (-)
• Length: 101 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KFZ74_RS19040 (KFZ74_19010)	4055037..4058417	+	3381	WP_238561285.1	cellulose synthase complex outer membrane protein BcsC	-
KFZ74_RS19045 (KFZ74_19015)	4058423..4058725	-	303	WP_238561286.1	BrnA antitoxin family protein	Antitoxin
KFZ74_RS19050 (KFZ74_19020)	4058706..4059005	-	300	WP_238561287.1	BrnT family toxin	Toxin
KFZ74_RS19055 (KFZ74_19025)	4059223..4060227	-	1005	WP_031279620.1	glycosyl hydrolase family 8	-
KFZ74_RS19060 (KFZ74_19030)	4060237..4060683	-	447	WP_058758083.1	cellulose biosynthesis protein BcsD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (9-90)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (11-93)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11951.42 Da
• Isoelectric Point: 6.9910

>T201847 WP_238561287.1 NZ_CP074350:c4059005-4058706 [Pantoea dispersa]
MQTEPEFEWDTTKAETNFRKHGIRFEVAARVFEDPFHLSMQDRYENGEYRWQTIGNVMGHVVILVAHTVRFETDVERIRI
ISARHATRIERRRYEQSQV

Nucleotide

• Length: 300 bp

>T201847 NZ_CP098792:c89476-89174 [Acinetobacter baumannii]
ATGTACTCAATATATACCACTGAAGTCTTTGATGACTGGTTCACCAAGTTAAAAGACCAGCAGGCAAAAAGACGCATACA
AGTCCGAATTGATCGGGTTGAAGATGGAAACTTTGGAGATACTGAGCCGGTCGGTGAAGGTGTTTCTGAATTACGTTTCT
TCTTTGGGCCAGGCTATAGGATTTATTACTGCAAGCAAGGGCAAAGGGTTGTTATTCTTTTAGCAGGCGGAGATAAGTCT
ACGCAAAGTAAAGATATAAAACTTGCCCTGCAATTGGCACAAGATTTAGAGGAGGAGCTATAA

Antitoxin

Protein

• Length: 101 a.a.
• Molecular weight: 11534.18 Da
• Isoelectric Point: 9.9975

>AT201847 WP_238561286.1 NZ_CP074350:c4058725-4058423 [Pantoea dispersa]
MSKVRFKRSELPPLTDKQQAELDALSRKQDSDIQFDDIAPLDDSFWQAAERGRFYRPVKTQASIRIDADILEWLKAPGKG
YQTRLNAILRAAMLRELQGK

Nucleotide

• Length: 303 bp

>AT201847 NZ_CP098792:c89173-88892 [Acinetobacter baumannii]
ATGGCTATTAAACTTCGCAAATGGGACAGTGCTGAGCATCTTAAAACAGAGGATGATATGCAGGCTTACTTACAAGCATG
TATTGAAGAATCTAATGGCGATGCCGCATTCATTGCAAAGGCTTTAGGTAACATTGCAAAAGCTAAAGGAATGGCTCAAT
TATCACGAGATACAGGCTTAGGCCGAGAAAGTCTTTATAAAGCACTTTCTGGTGATGTTAACCCTAGTTTTGATACTGTG
ATTAAAGTTGTAAAAGCACTGAATTTACGCTTAGCAATTTAA