Detailed information of TA system TA201841

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): sanaTA/AbiEii-DUF6088
• Location: 692283..693627
• Replicon: chromosome
• Accession: NZ_CP074350
• Organism: Pantoea dispersa strain YSD_J2

Toxin (Protein)

• Gene name: sanaT
• Uniprot ID: -
• Locus tag: KFZ74_RS03165
• Protein ID: WP_238561509.1
• Coordinates: 692671..693627 (+)
• Length: 319 a.a.

Antitoxin (Protein)

• Gene name: sanaA
• Uniprot ID: A0A8E1V821
• Locus tag: KFZ74_RS03160
• Protein ID: WP_058776421.1
• Coordinates: 692283..692678 (+)
• Length: 132 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KFZ74_RS03145 (KFZ74_03145)	687725..688810	-	1086	WP_238561506.1	DNA sulfur modification protein DndB	-
KFZ74_RS03150 (KFZ74_03150)	690012..691070	+	1059	WP_238561507.1	hypothetical protein	-
KFZ74_RS03155 (KFZ74_03155)	691218..692096	+	879	WP_238561508.1	AraC family transcriptional regulator	-
KFZ74_RS03160 (KFZ74_03160)	692283..692678	+	396	WP_058776421.1	DUF6088 family protein	Antitoxin
KFZ74_RS03165 (KFZ74_03165)	692671..693627	+	957	WP_238561509.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
KFZ74_RS03170 (KFZ74_03170)	693698..694027	+	330	WP_058757234.1	DUF1493 family protein	-
KFZ74_RS03175 (KFZ74_03175)	694065..694844	-	780	WP_058757197.1	NAD(P)H-dependent oxidoreductase	-
KFZ74_RS03180 (KFZ74_03180)	694935..695825	+	891	WP_238561510.1	LysR family transcriptional regulator	-
KFZ74_RS03185 (KFZ74_03185)	695840..696331	-	492	WP_058780921.1	DUF4411 family protein	-
KFZ74_RS03190 (KFZ74_03190)	696328..697410	-	1083	WP_215800646.1	ImmA/IrrE family metallo-endopeptidase	-
KFZ74_RS03195 (KFZ74_03195)	697739..698608	+	870	WP_238561511.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	675478..693627	18149

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (36-305)

Antitoxin

• Protein of unknown function DUF6088 (10-114)

Sequences

Toxin

Protein

• Length: 319 a.a.
• Molecular weight: 36260.73 Da
• Isoelectric Point: 5.9915

>T201841 WP_238561509.1 NZ_CP074350:692671-693627 [Pantoea dispersa]
MDDVIALFPDVADALGIESVAIVEKDFYIVELLRLLQPLSFGSHQLVFCGGTALSKAGIALNRMSEDVDIKLVPVADFFA
KNSRTQRKAIRKHIIAEITETLAASAFFRFDEAHPKTIRDEYRYSELPIRYPQKYAQVPCLRPFIKLEIIEATLLEPPEK
RDIQSLVSALTQQGVTVPDFPCATVLTTQAEKLVSMMRRTAAYIRRPQREDDASLVRHVYDNFCIASTHEIDLARLQAYV
RQCIKEDIERYGIQYPEFCTSPIAELRMGLEELAENPVHRQRYQQFVVPMVYGQSPASWEEAFARFRQTAIEVLSAAR

Nucleotide

• Length: 957 bp

>T201841 NZ_CP098778:c4488034-4487663 [Enterobacter hormaechei]
ATGGAGCACATGGCAGTGTTTGATACCAATATTCTCATTGATCTCTTCAACAACCGTGTTGAAGCTGCGGATGCGATTGA
GCATACCGCGTCGCATCGTGCCATCAGCTTAATTACCTGGATGGAAGTAATGGTGGGCGCTCGCAGGCATGGTCATGAAG
CGAAAACGGCAGCCGTTATGGGCGCTTTTGAAATTATTGATGTGTCTCGGGATATTGCGGAAAGAAGCGTTTTACTACGT
GAGAAGCATGGAATGAAACTGCCTGATGCTATCATTCTGGCCACAGCGCAGAGCAGAAAATGTCCGTTGATTTCTCGCAA
CACGAAAGATTTTGCGGGTATTGACGAGGTCCTTACGCCTTACCAGGTGTAG

Antitoxin

Protein

• Length: 132 a.a.
• Molecular weight: 14443.73 Da
• Isoelectric Point: 10.9938

>AT201841 WP_058776421.1 NZ_CP074350:692283-692678 [Pantoea dispersa]
MTIKARMQSRLKRSKRYVFTRDDFNDLAGYDQIGRVLRELVNEGQLLKVGYGVYTKARKNAITGKVMPAAPGGSAAVVIE
TLERLKVDYRLVGASDAYNSGKTTQIPASMQIKTSPRFKRTLSVGSSKLNG

Nucleotide

• Length: 396 bp

>AT201841 NZ_CP098778:c4488279-4488037 [Enterobacter hormaechei]
ATGAGCGTTTTGGCGGAACTTGATATGGGCAGAATACTTATCGATTTGTCTGATGACGTGATTCAACGTTTGGATAATCT
CAAGCAATTGCGAAATCAACCACGTGCTGAACTGCTTCGGGAAGCGATAGAACTGTATCTCGACCAGCAGAGTTCTTCTG
TTATCCGAAATGCGCTTGGTCTGTGGGGAGACAGAAAAGAGGACGGGCTTGAGTATGAACGCAAGCTGCGTGAGGAGTGG
TAA