Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
| Location | 1369488..1370265 | Replicon | chromosome |
| Accession | NZ_CP074346 | ||
| Organism | Pasteurella atlantica strain NVI-9100 | ||
Toxin (Protein)
| Gene name | TacT3 | Uniprot ID | - |
| Locus tag | KGI96_RS06435 | Protein ID | WP_211599247.1 |
| Coordinates | 1369765..1370265 (+) | Length | 167 a.a. |
Antitoxin (Protein)
| Gene name | TacA3 | Uniprot ID | - |
| Locus tag | KGI96_RS06430 | Protein ID | WP_211599246.1 |
| Coordinates | 1369488..1369772 (+) | Length | 95 a.a. |
Genomic Context
Location: 1366839..1368662 (1824 bp)
Type: Others
Protein ID: WP_211599244.1
Type: Others
Protein ID: WP_211599244.1
Location: 1369488..1369772 (285 bp)
Type: Antitoxin
Protein ID: WP_211599246.1
Type: Antitoxin
Protein ID: WP_211599246.1
Location: 1369765..1370265 (501 bp)
Type: Toxin
Protein ID: WP_211599247.1
Type: Toxin
Protein ID: WP_211599247.1
Location: 1370390..1370668 (279 bp)
Type: Others
Protein ID: WP_211599248.1
Type: Others
Protein ID: WP_211599248.1
Location: 1370706..1370870 (165 bp)
Type: Others
Protein ID: WP_211599249.1
Type: Others
Protein ID: WP_211599249.1
Location: 1364962..1365639 (678 bp)
Type: Others
Protein ID: WP_211599242.1
Type: Others
Protein ID: WP_211599242.1
Location: 1365629..1366663 (1035 bp)
Type: Others
Protein ID: WP_211599243.1
Type: Others
Protein ID: WP_211599243.1
Location: 1368848..1369135 (288 bp)
Type: Others
Protein ID: WP_211599245.1
Type: Others
Protein ID: WP_211599245.1
Location: 1371347..1372165 (819 bp)
Type: Others
Protein ID: Protein_1262
Type: Others
Protein ID: Protein_1262
Location: 1372259..1374202 (1944 bp)
Type: Others
Protein ID: WP_211599250.1
Type: Others
Protein ID: WP_211599250.1
Location: 1374584..1374883 (300 bp)
Type: Others
Protein ID: WP_229577136.1
Type: Others
Protein ID: WP_229577136.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KGI96_RS06410 (KGI96_06410) | 1364962..1365639 | - | 678 | WP_211599242.1 | methionine ABC transporter permease | - |
| KGI96_RS06415 (KGI96_06415) | 1365629..1366663 | - | 1035 | WP_211599243.1 | methionine ABC transporter ATP-binding protein MetN | - |
| KGI96_RS06420 (KGI96_06420) | 1366839..1368662 | + | 1824 | WP_211599244.1 | ATP-binding protein | - |
| KGI96_RS06425 (KGI96_06425) | 1368848..1369135 | - | 288 | WP_211599245.1 | 50S ribosomal protein L25 | - |
| KGI96_RS06430 (KGI96_06430) | 1369488..1369772 | + | 285 | WP_211599246.1 | DUF1778 domain-containing protein | Antitoxin |
| KGI96_RS06435 (KGI96_06435) | 1369765..1370265 | + | 501 | WP_211599247.1 | N-acetyltransferase | Toxin |
| KGI96_RS06440 (KGI96_06440) | 1370390..1370668 | + | 279 | WP_211599248.1 | hypothetical protein | - |
| KGI96_RS06445 (KGI96_06445) | 1370706..1370870 | + | 165 | WP_211599249.1 | hypothetical protein | - |
| KGI96_RS06455 (KGI96_06455) | 1371347..1372165 | - | 819 | Protein_1262 | site-specific integrase | - |
| KGI96_RS06460 (KGI96_06460) | 1372259..1374202 | - | 1944 | WP_211599250.1 | MobH family relaxase | - |
| KGI96_RS06465 (KGI96_06465) | 1374584..1374883 | - | 300 | WP_229577136.1 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 167 a.a. Molecular weight: 18651.68 Da Isoelectric Point: 9.4848
>T201820 WP_211599247.1 NZ_CP074346:1369765-1370265 [Pasteurella atlantica]
MPKYIEEPLDKAHNRKNFDCGNEELNTFLRCYAGQSHKKGTAKTYLTLDKETKKIIGFYSITLTSIEYNQIPKSFQKGLS
RHQVPLFILARLGVDVSEQNKGIGGVLLYKAIERCIKVSEEVGGIGLLIEAKDDDVAKWYSKFGAISLPDKPLSLILPFS
TIKNIK
MPKYIEEPLDKAHNRKNFDCGNEELNTFLRCYAGQSHKKGTAKTYLTLDKETKKIIGFYSITLTSIEYNQIPKSFQKGLS
RHQVPLFILARLGVDVSEQNKGIGGVLLYKAIERCIKVSEEVGGIGLLIEAKDDDVAKWYSKFGAISLPDKPLSLILPFS
TIKNIK
Download Length: 501 bp
>T201820 NZ_CP098777:1763925-1764221 [Cronobacter sakazakii]
ATGCAGAAGCATATCGGCAGTTTTCGTGACGCCTGGCTGGCGGCGTTTTTCGTGTATTCGACGCCACACCGCAACATCCC
GGCGGAGATTCATACCACACTGGCGCGCAAGCTCGACATCATCAACGCAGCAACGTCATACCGCGATCTTCGCTCGCCGC
CTGGCAACCGCTTTGAGGCGCTGAGCGGTAAATTGCAGGGGTATTCATCGATTCGGGTCAACCATCACTACCGCCTGATT
TTCAGATGGGTGGAAGGCAAAGCGGAAGATCTCTATTTAGATCCGCATGATTACTGA
ATGCAGAAGCATATCGGCAGTTTTCGTGACGCCTGGCTGGCGGCGTTTTTCGTGTATTCGACGCCACACCGCAACATCCC
GGCGGAGATTCATACCACACTGGCGCGCAAGCTCGACATCATCAACGCAGCAACGTCATACCGCGATCTTCGCTCGCCGC
CTGGCAACCGCTTTGAGGCGCTGAGCGGTAAATTGCAGGGGTATTCATCGATTCGGGTCAACCATCACTACCGCCTGATT
TTCAGATGGGTGGAAGGCAAAGCGGAAGATCTCTATTTAGATCCGCATGATTACTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10645.20 Da Isoelectric Point: 6.4694
>AT201820 WP_211599246.1 NZ_CP074346:1369488-1369772 [Pasteurella atlantica]
MARAINTTSDRISIRISRDDKEILQKATLLSKTTITDFVLKHVLYNAKEIVKEHEESSLSKNDLAFIMDLLDNPPAPNER
LMKAAKTAQDLYDA
MARAINTTSDRISIRISRDDKEILQKATLLSKTTITDFVLKHVLYNAKEIVKEHEESSLSKNDLAFIMDLLDNPPAPNER
LMKAAKTAQDLYDA
Download Length: 285 bp
>AT201820 NZ_CP098777:1764254-1764595 [Cronobacter sakazakii]
ATGAAACAGGCAACCAGAAAGCCCACGACGCCCGGCGAGATCCTGGTGTACGAATACCTGGAGCCGCTCGGCCTTAAAAT
TAACGAGGTGGCGGAGATGCTTTGCGTCCATCGTAATAGCGTGAGCGCGCTGGTGAACAATAACCGCAAACTCACTACAG
ATATGGCGTTTCGTCTGGCAAAAGCGTTTGGAACCTCAGTTGATTTCTGGCTTAACCTGCAGGCGGCTGTCGATCTGTGG
GAGGTCGAGAATGATATGCGCATTCAGGAAGCGTTCAGCCGCATCGTACCCGCTGCGGAGTTTATCGCCCGGCGCGACGC
GCAGAAGAAAGCTGTCGCCTGA
ATGAAACAGGCAACCAGAAAGCCCACGACGCCCGGCGAGATCCTGGTGTACGAATACCTGGAGCCGCTCGGCCTTAAAAT
TAACGAGGTGGCGGAGATGCTTTGCGTCCATCGTAATAGCGTGAGCGCGCTGGTGAACAATAACCGCAAACTCACTACAG
ATATGGCGTTTCGTCTGGCAAAAGCGTTTGGAACCTCAGTTGATTTCTGGCTTAACCTGCAGGCGGCTGTCGATCTGTGG
GAGGTCGAGAATGATATGCGCATTCAGGAAGCGTTCAGCCGCATCGTACCCGCTGCGGAGTTTATCGCCCGGCGCGACGC
GCAGAAGAAAGCTGTCGCCTGA