Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 1295486..1295988 Replicon chromosome
Accession NZ_CP074346
Organism Pasteurella atlantica strain NVI-9100

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag KGI96_RS06105 Protein ID WP_211598264.1
Coordinates 1295486..1295740 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KGI96_RS06110 Protein ID WP_211598266.1
Coordinates 1295737..1295988 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGI96_RS06080 (KGI96_06080) 1290939..1291853 - 915 WP_211598253.1 glycosyltransferase family 8 protein -
KGI96_RS06085 (KGI96_06085) 1291863..1292633 - 771 WP_211598256.1 glycosyltransferase family 25 protein -
KGI96_RS06090 (KGI96_06090) 1292847..1293893 - 1047 WP_211598258.1 extracellular solute-binding protein -
KGI96_RS06095 (KGI96_06095) 1294056..1294772 + 717 WP_211598260.1 DnaA regulatory inactivator Hda -
KGI96_RS06100 (KGI96_06100) 1294774..1295466 - 693 WP_211598262.1 16S rRNA pseudouridine(516) synthase RsuA -
KGI96_RS06105 (KGI96_06105) 1295486..1295740 - 255 WP_211598264.1 Txe/YoeB family addiction module toxin Toxin
KGI96_RS06110 (KGI96_06110) 1295737..1295988 - 252 WP_211598266.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
KGI96_RS06115 (KGI96_06115) 1296112..1296825 - 714 WP_211598268.1 hypothetical protein -
KGI96_RS06120 (KGI96_06120) 1296845..1297555 - 711 WP_211598270.1 bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG -
KGI96_RS06125 (KGI96_06125) 1297653..1298291 - 639 WP_211598273.1 DUF2057 domain-containing protein -
KGI96_RS06130 (KGI96_06130) 1298436..1299323 + 888 WP_211598275.1 CNNM family magnesium/cobalt transport protein CorC -
KGI96_RS06135 (KGI96_06135) 1299326..1300852 + 1527 WP_213156391.1 apolipoprotein N-acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10092.68 Da        Isoelectric Point: 9.7073

>T201819 WP_211598264.1 NZ_CP074346:c1295740-1295486 [Pasteurella atlantica]
MIVCFTDKGWEDYLYWQETDKKTLKRINSLIKEIKRSPFIGKGKPEPLKHSLSGFWSRRITEEHRLVYRVSEDALSIVAC
RYHY

Download         Length: 255 bp

>T201819 NZ_CP098777:c1094753-1094535 [Cronobacter sakazakii]
ATGACGACCAAACCATTAACCAAAACCGATTATTTAATGCGACTGAGACGTTGTCAGACAATTGACACGCTTGAGCGCGT
TATTGAAAAAAATAAATATGAATTATCCGACAACGAACTGGCGGTATTTTATTCAGCGGCGGATCATCGTCTGGCTGAAC
TGACGATGAATAAACTCTACGATAAAATTCCGACCGCCGTGTGGAAGTTCGTTCGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9428.74 Da        Isoelectric Point: 4.4693

>AT201819 WP_211598266.1 NZ_CP074346:c1295988-1295737 [Pasteurella atlantica]
MQVMTYTEARQNLAQTMTATAENCEPVLITRSNNESCVLISLREYEALEETAYLLRSPANAKHLLESIEELKLGNVTKRE
LIE

Download         Length: 252 bp

>AT201819 NZ_CP098777:c1095154-1094780 [Cronobacter sakazakii]
ATGGACGAATACTCACCAAAACGGCATGATATAGCGCAGCTTAAATTTCTTTGCGAAAGCCTGTATCATGATTGCCTTGC
CACGCTCGGCGAAAACCAGCATGGCTGGGTTAACGACCCCACTTCCGCCGTTAACCTGCAACTCAACGACTTGATTGAGC
ATATTGCCAGCTTCGGCCTGAATTATAAAATTAAGCATGAAGATGACGCAGCTCTCATTGAGCAATTAGATGAATATCTG
GATGATACCTTTATGCTGTTCAGCAATTACGGTATCAATGCGCAAGATTTACAAAAATGGCGCAAGTCCGGAAACAGGCT
TTTCCGGTGTTTTGTAAACGCCAGCAAAGAAAACCCTGTAAGCTTGTCTTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References