Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 907398..907999 Replicon chromosome
Accession NZ_CP074346
Organism Pasteurella atlantica strain NVI-9100

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KGI96_RS04220 Protein ID WP_211598152.1
Coordinates 907697..907999 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KGI96_RS04215 Protein ID WP_211598149.1
Coordinates 907398..907694 (-) Length 99 a.a.

Genomic Context

KGI96_RS04225KGI96_RS04230KGI96_RS04235KGI96_RS04205KGI96_RS04210KGI96_RS04215KGI96_RS04220
Location: 908255..908782 (528 bp)
Type: Others
Protein ID: WP_211598155.1
Location: 909058..910257 (1200 bp)
Type: Others
Protein ID: WP_211598158.1
Location: 910321..912465 (2145 bp)
Type: Others
Protein ID: WP_211598160.1
Location: 905229..905891 (663 bp)
Type: Others
Protein ID: WP_211598120.1
Location: 906033..907382 (1350 bp)
Type: Others
Protein ID: WP_211598147.1
Location: 907398..907694 (297 bp)
Type: Antitoxin
Protein ID: WP_211598149.1
Location: 907697..907999 (303 bp)
Type: Toxin
Protein ID: WP_211598152.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KGI96_RS04205 (KGI96_04205)905229..905891-663WP_211598120.1hypothetical protein-
KGI96_RS04210 (KGI96_04210)906033..907382-1350WP_211598147.1metalloprotease PmbA-
KGI96_RS04215 (KGI96_04215)907398..907694-297WP_211598149.1putative addiction module antidote proteinAntitoxin
KGI96_RS04220 (KGI96_04220)907697..907999-303WP_211598152.1type II toxin-antitoxin system RelE/ParE family toxinToxin
KGI96_RS04225 (KGI96_04225)908255..908782+528WP_211598155.1ribosome biogenesis factor YjgA-
KGI96_RS04230 (KGI96_04230)909058..910257+1200WP_211598158.1acetate kinase-
KGI96_RS04235 (KGI96_04235)910321..912465+2145WP_211598160.1phosphate acetyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(48-91)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11297.29 Da        Isoelectric Point: 10.7827

>T201818 WP_211598152.1 NZ_CP074346:c907999-907697 [Pasteurella atlantica]
MKKISVRTTPIFDKWLDSLKDFRAVARISARIDRLKMGNLGDHKSVGRGIFELRIPEGKGYRVYFKNYNGVLVILLCGGD
KTTQSKDIKQANKIAKELGV

Download         Length: 303 bp

>T201818 NZ_CP098775:c139450-138131 [Cronobacter sakazakii]
ATGCGCCGCACGTCGCGTTTAGCGCTCTGGATGAACGGCATCCCGGTCGGTTACTGGGATAAACACAACGGCGAAGACCG
GCTGACCTATCTGCCGGAGTGGATTGCCGATCCGCAGGGCAGGCCGCTGTCGCTGTCGCTGCCGTTCACGCCCGGTAATC
AGTCATACCGTGGCGCGCAGGTGCGCGATTACTTCGACAACCTGCTGCCGGACAGCGAAAACATCCGGCGGCGGCTGGCG
ATGCGTTACCGGGCGCAGAGCCTGGAGCCGTTCGATCTGCTGGCGGAGCTGGGGCGCGACTGTGTGGGGGCCATCCAGCT
GTTGCCCGCCGGTGAAGCGCCGGAGGGGCTTTTTACCATCCGCGCCCGTCCACTCTCCACAGTAGATATTGCCGCGATGC
TGCGCCACACCGCAGAGGCGTTCCCCGGACAGCATGGCGGCGAAGAGGAGCTGCGGCTCTCCATTGCGGGCGCGCAGGAG
AAAACCGCGCTGCTGTGGCACGAAGACCAGTGGTGCCTGCCGGAGGGCAACACGCCCACCACGCATATTTTCAAACTGCC
GCTGGGGCTGGTGGGCAACATGCAGGCGGATATGCGCACCTCCATTGAAAACGAATGGCTCTGCGCGCAGCTACTGGCGG
CCTGGGATATTCCGGTCGCGCGCACGCAGATGGCGCAGTTCGAAGAGCAAAAAGTGCTGATTGTTGAGCGCTTCGACCGC
CGTCTGTCCGGTGATGGCCGGTGGTGGCTGCGTCTGCCGCAGGAGGATATGTGCCAGGCGCTGGGCGTTTCGCCGCTGCG
TAAATATCAGGCCGACGGCGGGCCGGGCATCGGTGATATCATGACGGTTCTGAGCCGTTCAGAAAACGCGCAGGCGGATC
GCGCGAATTTCTTCCGCGCGCAGATTATTTTCTGGATCCTCGCCGCGACCGACGGCCACGCCAAGAATTTCAGCATCGCG
CACCTGCCCGGCAACCGTTACCACCTGACGCCGCTTTACGACGTGCTCTCCGCCTGGCCGGTCATCGGGCCGGGTAATAA
CCAGATCGCGTGGCAGAAGTGCAAGCTGGCGATGGCGGTGCGCGGCAGCAGTAACTATTACCACCTGAGCCAGATCCGCC
GCCGTCACTGGCTGCGCCAGGGCGAGCTTGCCGGGCTGTCGGCGGCGCAGGTCAACGACATGATTGATGCGCTGACAGCC
AGCGCGCCTGCGGTGATCGCGCGCGTGGCCGACGCGCTCCCGGTGGATTTCCCCGCCTCTCTGGCCGACGTTATTTTTAA
CGGCATGCGCCAGCAGTGCGCGCGCCTCGCGGCCGCATAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10941.62 Da        Isoelectric Point: 4.8411

>AT201818 WP_211598149.1 NZ_CP074346:c907694-907398 [Pasteurella atlantica]
MKLDDLKEFDASKYLVDEESIAIYVNEMLESGDLKALPLALGTVSKARNMSELSRKTGISRKGLYQALSEDGNPSFDTVL
KVMQALNLTFEIKQKQVI

Download         Length: 297 bp

>AT201818 NZ_CP098775:c139734-139453 [Cronobacter sakazakii]
ATGAACACCCGGTATCCACTGAAAACGCTTAGCCAGCTGCGCCCGCTGCTGGTGGGCTTTCGTAAAAAACAGGGGCTGAC
CCAGAAAGAAGTTTCGGCGCGGCTTGGCGTCACGCAGCAAACCTATGCGCGGCTGGAGGCGAACCCCGAGACGGCCAGCA
TCGAGCGCCTGTTCCGCGTCTTTAACGTGCTGGGCATTGAGATAACGCTGTGCGAAACGCAGGCGGCAGAGTCTGACGCG
CCCGCGCGTGACGATTCGCCTGCCCGTCGCGAGGCGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References