Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2151937..2152847 Replicon chromosome
Accession NZ_CP074200
Organism Halomonas sp. FeN2

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag KF947_RS09795 Protein ID WP_133731827.1
Coordinates 2152383..2152847 (+) Length 155 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag KF947_RS09790 Protein ID WP_227406130.1
Coordinates 2151937..2152386 (+) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KF947_RS09770 (KF947_09750) 2148569..2148889 - 321 WP_227406127.1 urease subunit beta -
KF947_RS09775 (KF947_09755) 2148914..2149216 - 303 WP_022521353.1 urease subunit gamma -
KF947_RS09780 (KF947_09760) 2149254..2150138 - 885 WP_227406128.1 urease accessory protein UreD -
KF947_RS09785 (KF947_09765) 2150366..2151727 - 1362 WP_227406129.1 diguanylate cyclase -
KF947_RS09790 (KF947_09770) 2151937..2152386 + 450 WP_227406130.1 DUF2384 domain-containing protein Antitoxin
KF947_RS09795 (KF947_09775) 2152383..2152847 + 465 WP_133731827.1 RES family NAD+ phosphorylase Toxin
KF947_RS09800 (KF947_09780) 2153090..2154058 + 969 WP_227406131.1 zinc ABC transporter substrate-binding protein -
KF947_RS09805 (KF947_09785) 2154082..2154864 + 783 WP_133731829.1 ABC transporter ATP-binding protein -
KF947_RS09810 (KF947_09790) 2154868..2155974 + 1107 WP_227406132.1 metal ABC transporter permease -
KF947_RS09815 (KF947_09795) 2155971..2156891 + 921 WP_227406133.1 metal ABC transporter permease -
KF947_RS09820 (KF947_09800) 2156989..2157696 - 708 WP_227406134.1 urea ABC transporter ATP-binding subunit UrtE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(6-149)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(96-146)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 16961.27 Da        Isoelectric Point: 4.1865

>T201804 WP_133731827.1 NZ_CP074200:2152383-2152847 [Halomonas sp. FeN2]
MNEVTAYRLVKRKFQETAFDGEGARLYGGRWNSPGNACVYVASSESLALLEIMVHLESYRLLNAYALLRLTLPAESILSV
GEEDLPENWQEAPAPAETAELGDGWLASKQSLALAVPSVVVPRELNYMLNPADPLFDQIVTTAEALPFQPDPRL

Download         Length: 465 bp

>T201804 NZ_CP098770:329638-330006 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16713.23 Da        Isoelectric Point: 10.3453

>AT201804 WP_227406130.1 NZ_CP074200:2151937-2152386 [Halomonas sp. FeN2]
MDIHFTQYQPPKALASGFWQQIGLPARGRKLHELLHQGVEYRVYPRLAKVSGIEQKALARYVDIPSATLSRRAKSGRFKM
AESDRLYRFAELFKAALDLFEGDAESARAWLLKPNAGLGGRRPVEMSATSAEYQTVLNLIGRLEHGVSV

Download         Length: 450 bp

>AT201804 NZ_CP098770:329420-329641 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References