Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/ElaA-DUF1778
Location 65289..66040 Replicon plasmid pJBIWA002_2
Accession NZ_CP074178
Organism Enterobacter asburiae strain JBIWA002

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag KGP20_RS24030 Protein ID WP_223540748.1
Coordinates 65558..66040 (+) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag KGP20_RS24025 Protein ID WP_223540749.1
Coordinates 65289..65567 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP20_RS24020 (KGP20_23895) 62914..65151 - 2238 WP_223605351.1 type IV conjugative transfer system coupling protein TraD -
KGP20_RS24025 (KGP20_23900) 65289..65567 + 279 WP_223540749.1 DUF1778 domain-containing protein Antitoxin
KGP20_RS24030 (KGP20_23905) 65558..66040 + 483 WP_223540748.1 GNAT family N-acetyltransferase Toxin
KGP20_RS24035 (KGP20_23910) 66078..66815 - 738 WP_223540801.1 conjugal transfer complement resistance protein TraT -
KGP20_RS24040 (KGP20_23915) 66985..67554 - 570 WP_223605352.1 protein traS -
KGP20_RS24045 (KGP20_23920) 67628..68410 - 783 WP_032666787.1 IS21-like element ISSen3 family helper ATPase IstB -
KGP20_RS24050 (KGP20_23925) 68407..69429 - 1023 WP_223540652.1 IS21 family transposase -
KGP20_RS24055 (KGP20_23930) 69536..69943 - 408 WP_223540833.1 ammonia monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..71219 71219


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(46-144)

Antitoxin

Vibrio phage ICP1, Orf50

(3-91)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17378.95 Da        Isoelectric Point: 8.4775

>T201779 WP_223540748.1 NZ_CP074178:65558-66040 [Enterobacter asburiae]
MGISAPEPLNSGHNIADFCCTEPGLNEWLKKKAHKNHSTGISRVYVICAENSHRVIGYYCLSTGSVQRNTAPGAYRRNAP
ESLPVIVLGRLAVDQAYSGQGLGVALLKDAVYRTEHIALQVGVKALVVHALSEEVSSFYTRFGFDASVVHPLTLLYPVKL

Download         Length: 483 bp

>T201779 NZ_CP098758:c1484320-1483952 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10495.88 Da        Isoelectric Point: 4.5141

>AT201779 WP_223540749.1 NZ_CP074178:65289-65567 [Enterobacter asburiae]
MKTEAREAPINIRARTSQRDLIDMAASLVSKSRTDFMLDAACREAQDILLDQRLFILDNAQYESFIAELDAPVTAERQAR
IDDLMGHKSPWE

Download         Length: 279 bp

>AT201779 NZ_CP098758:c1484538-1484317 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References