Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 83518..84053 Replicon plasmid pJBIWA003_2
Accession NZ_CP074172
Organism Enterobacter sp. JBIWA003

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KGP25_RS26010 Protein ID WP_223540734.1
Coordinates 83518..83805 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KGP25_RS26015 Protein ID WP_223540735.1
Coordinates 83802..84053 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP25_RS25995 (KGP25_25860) 80807..81505 - 699 WP_223540731.1 type VI secretion system protein TssL, short form -
KGP25_RS26000 (KGP25_25865) 81794..82426 - 633 WP_223540732.1 recombinase family protein -
KGP25_RS26005 (KGP25_25870) 82831..83166 - 336 WP_223540733.1 hypothetical protein -
KGP25_RS26010 (KGP25_25875) 83518..83805 - 288 WP_223540734.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KGP25_RS26015 (KGP25_25880) 83802..84053 - 252 WP_223540735.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KGP25_RS26020 (KGP25_25885) 84225..84542 - 318 WP_223540736.1 hypothetical protein -
KGP25_RS26025 (KGP25_25890) 84898..85185 - 288 WP_223540737.1 type II toxin-antitoxin system RelE/ParE family toxin -
KGP25_RS26030 (KGP25_25895) 85182..85433 - 252 WP_172686957.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
KGP25_RS26035 (KGP25_25900) 85793..85984 - 192 WP_176454398.1 hypothetical protein -
KGP25_RS26040 (KGP25_25905) 86092..86394 - 303 WP_181244197.1 hypothetical protein -
KGP25_RS26045 (KGP25_25910) 86391..87017 - 627 WP_223540738.1 ParA family plasmid-partitioning AAA ATPase -
KGP25_RS26050 (KGP25_25915) 87187..88461 - 1275 WP_223540739.1 Y-family DNA polymerase -
KGP25_RS26055 (KGP25_25920) 88461..88538 - 78 Protein_81 peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..116363 116363


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11114.14 Da        Isoelectric Point: 10.5832

>T201754 WP_223540734.1 NZ_CP074172:c83805-83518 [Enterobacter sp. JBIWA003]
MTYKVKFRDDALKEWLKLDTVIQQQFAKKLKKCSENPHIPSAKLRGIKDCYKIKLRASGFRLVYQVINDQLIIAVVAVGK
RERSDVYNLASERMR

Download         Length: 288 bp

>T201754 NZ_CP098743:474662-474772 [Enterococcus faecalis]
TTGTCCGTTGAAGCAGCGCTAGGACTGATGATTGGTTTTGCAACACTTGTTGTGACCATTATCTTCGGTATCTTAGCGCT
TGTCTTAGACAACAAAAATAACCGTTCATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9199.45 Da        Isoelectric Point: 4.2975

>AT201754 WP_223540735.1 NZ_CP074172:c84053-83802 [Enterobacter sp. JBIWA003]
MPNIILSDTSASVSELKKNPMATVSSGDGYPVAILNRNQPAFYCVPAKLYEKMLDALDDQELVKLVAERSNQQLHDVDLD
SYL

Download         Length: 252 bp

>AT201754 NZ_CP098743:c474888-474683 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACCAGTTATAAGAACTGGTGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References