Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 62827..63362 Replicon plasmid pJBIWA005_2
Accession NZ_CP074161
Organism Enterobacter sp. JBIWA005

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KGP22_RS23795 Protein ID WP_223540737.1
Coordinates 62827..63114 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KGP22_RS23800 Protein ID WP_172686957.1
Coordinates 63111..63362 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP22_RS23755 (KGP22_23630) 57995..58405 - 411 WP_123061016.1 PIN domain-containing protein -
KGP22_RS23760 (KGP22_23635) 58402..58632 - 231 WP_123061017.1 type II toxin-antitoxin system VapB family antitoxin -
KGP22_RS23765 (KGP22_23640) 59247..59609 + 363 WP_223582714.1 hypothetical protein -
KGP22_RS23770 (KGP22_23645) 59640..59969 + 330 WP_223582716.1 hypothetical protein -
KGP22_RS23775 (KGP22_23650) 60017..60415 + 399 WP_223582718.1 hypothetical protein -
KGP22_RS23780 (KGP22_23655) 60520..61299 + 780 WP_223582720.1 site-specific integrase -
KGP22_RS23785 (KGP22_23660) 61699..62001 - 303 WP_172686959.1 hypothetical protein -
KGP22_RS23790 (KGP22_23665) 62154..62471 - 318 WP_223540736.1 hypothetical protein -
KGP22_RS23795 (KGP22_23670) 62827..63114 - 288 WP_223540737.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KGP22_RS23800 (KGP22_23675) 63111..63362 - 252 WP_172686957.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KGP22_RS23805 (KGP22_23680) 63722..63913 - 192 WP_176454398.1 hypothetical protein -
KGP22_RS23810 (KGP22_23685) 63997..64299 - 303 WP_181244197.1 hypothetical protein -
KGP22_RS23815 (KGP22_23690) 64296..64922 - 627 WP_223540738.1 ParA family plasmid-partitioning AAA ATPase -
KGP22_RS23820 (KGP22_23695) 65140..65547 - 408 Protein_83 DUF4113 domain-containing protein -
KGP22_RS23825 (KGP22_23700) 65523..65900 + 378 WP_223582722.1 DUF1380 domain-containing protein -
KGP22_RS23830 (KGP22_23705) 66052..66507 + 456 WP_223582723.1 hypothetical protein -
KGP22_RS23835 (KGP22_23710) 66795..67352 + 558 WP_223582724.1 single-stranded DNA-binding protein -
KGP22_RS23840 (KGP22_23715) 67404..67637 + 234 WP_223540827.1 DUF905 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..92286 92286


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11142.11 Da        Isoelectric Point: 10.4701

>T201713 WP_223540737.1 NZ_CP074161:c63114-62827 [Enterobacter sp. JBIWA005]
MTYTVKFRDDALKEWQKLDKPIQQQFAKKLKKCSENPHIPSAKLRGIKDCYKIKLRASGFRLVYQVIDDQLIIAVVAVGK
RERSEVYNLASERMR

Download         Length: 288 bp

>T201713 NZ_CP098724:1877850-1878308 [Yersinia ruckeri]
GTGATGCTCTACCGGATAGTTCACAACCGTTACCTGGCAACGGCCTGGACCGGATATGGCGCAGAAACCTATGGTGGCCG
CTGGAATCATAAAGGCCATGCGGCGATTTATCTGGCCAGTAGCGTTTCTCTGGCGATGCTCGAAACACTGGTGCATGTAG
AAGATAGCGCGACGCTGAACGATTTTAATCTATTTCAGATAACCATTCCCGATAATGCAATTATGGTACTGCAACAGCAA
GATTGGCCACGTGGATGGCGAGATGACCCCACCCCCGTGGCCACCATGGACATCGGCACCGAATGGATTGGTTCAGTATC
ATCTGTCGGTCTGCTGGTACCATCCACGTTAGTCCCTTTGGAAAGAAATATGCTGGTGAATCCTAAACACCGCGATTTCG
CCTCGTGCCTGAAAAGCATCAATCCACTGACGTTCAGTTTTGATCCTCGTCTAAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9130.34 Da        Isoelectric Point: 4.0780

>AT201713 WP_172686957.1 NZ_CP074161:c63362-63111 [Enterobacter sp. JBIWA005]
MPNIILSDTSASVSELKKNPMATVSAGDGYPVAILNRNQPAFYCVPAELYEKMLDALDDQELVKLVAERSSQTLHDVDLD
SYL

Download         Length: 252 bp

>AT201713 NZ_CP098724:1877390-1877836 [Yersinia ruckeri]
ATGAGAACTTATCACCCAAGCCCGATGGCCAAAGTCAGCGCACTATGGCGTGAGATTGGTCTACCCGCCAGTCGTGGCAC
CGCTTTGGTGGACAGCATAAAACTGGGATTTACTGTGGATGTGATCGACACTATACATTTATGGGCTGATATGCCTAAAT
CTGAAATATTACGCGCTACGGGCATTCCGAGCCGCAGTCTGACGCGCCGTCGTACCCATGATGGGCGTTTTACCCCGGAA
GAAAGCGAACGTATTGCACGGTTTGTCCGGGTTATGGATGCGGCGGTAGATTTGTTCGGTGGTGACCGCACCAAAGCAAC
CGCATGGATGTCGATGCCGGTCAAAGGGCTGGGTAATCGAACGCCCGATTCACTGCTGGAAACCGAAACCGGTGCGTTGG
AAATCTGCGACCTGATTGGTCGTCTCGAACATGGGGTCTTTTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References