Detailed information of TA system TA201704

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yeeUV (cbtA-cbeA)/CbtA-CbeA
• Location: 3158137..3158925
• Replicon: chromosome
• Accession: NZ_CP074159
• Organism: Enterobacter sp. JBIWA005

Toxin (Protein)

• Gene name: yeeV
• Uniprot ID: -
• Locus tag: KGP22_RS14985
• Protein ID: WP_223579914.1
• Coordinates: 3158548..3158925 (+)
• Length: 126 a.a.

Antitoxin (Protein)

• Gene name: yeeU
• Uniprot ID: -
• Locus tag: KGP22_RS14980
• Protein ID: WP_282443075.1
• Coordinates: 3158137..3158496 (+)
• Length: 120 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KGP22_RS14935 (KGP22_14870)	3153905..3154456	+	552	WP_223579887.1	hypothetical protein	-
KGP22_RS14940	3154462..3154977	+	516	WP_223579890.1	hypothetical protein	-
KGP22_RS14945 (KGP22_14880)	3155011..3155301	+	291	WP_223579894.1	hypothetical protein	-
KGP22_RS14950 (KGP22_14885)	3155307..3155618	+	312	WP_223579897.1	hypothetical protein	-
KGP22_RS14955 (KGP22_14890)	3155828..3156646	+	819	WP_223579900.1	DUF932 domain-containing protein	-
KGP22_RS14960 (KGP22_14895)	3156646..3156900	+	255	WP_223579903.1	hypothetical protein	-
KGP22_RS14965 (KGP22_14900)	3156917..3157390	+	474	WP_223579906.1	antirestriction protein	-
KGP22_RS14970 (KGP22_14905)	3157401..3157880	+	480	WP_223579910.1	DNA repair protein RadC	-
KGP22_RS14975 (KGP22_14910)	3157892..3158113	+	222	WP_048961313.1	DUF987 domain-containing protein	-
KGP22_RS14980 (KGP22_14915)	3158137..3158496	+	360	WP_282443075.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
KGP22_RS14985 (KGP22_14920)	3158548..3158925	+	378	WP_223579914.1	TA system toxin CbtA family protein	Toxin
KGP22_RS14990 (KGP22_14925)	3158922..3159413	+	492	WP_223579917.1	DUF5983 family protein	-
KGP22_RS14995 (KGP22_14930)	3159437..3159640	+	204	WP_223579920.1	hypothetical protein	-
KGP22_RS15000 (KGP22_14935)	3159787..3160749	-	963	WP_223579923.1	glycosyltransferase	-
KGP22_RS15005 (KGP22_14940)	3161212..3162045	+	834	WP_223579926.1	DUF4942 domain-containing protein	-
KGP22_RS15010 (KGP22_14945)	3162314..3163237	-	924	WP_111965977.1	D-alanyl-D-alanine endopeptidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (11-112)

Antitoxin

• Antitoxin CbeA (15-114)

Sequences

Toxin

Protein

• Length: 126 a.a.
• Molecular weight: 13951.89 Da
• Isoelectric Point: 7.2917

>T201704 WP_223579914.1 NZ_CP074159:3158548-3158925 [Enterobacter sp. JBIWA005]
MQTQLLSPTWEAPTHPSPVEVWQRLLSHLLDRHYGLTLNDTPFGIDGVIQEHIDAGISLCDAVNFIVEKYDLVRTDRRGF
SAETQSPLLTRIDILRARKATCLMQRTGYKAVTCAISGRSSGGQQ

Nucleotide

• Length: 378 bp

>T201704 NZ_CP098723:1560989-1561082 [Yersinia ruckeri]
TAAGCCTGCATGAAATGCCAACTTTTAGCGCACGGCTCTATCCCAAGAGCCATTTCCCTGGACCGAATATAGGATTCGTA
TTCGGTCTTTTTTT

Antitoxin

Protein

• Length: 120 a.a.
• Molecular weight: 13127.86 Da
• Isoelectric Point: 6.6280

>AT201704 WP_282443075.1 NZ_CP074159:3158137-3158496 [Enterobacter sp. JBIWA005]
MSNQTPAAPHDISEPWWGLRRSVTPCLGARLVQEGNRLHYLADRASITGTFSDADLRHLDQAFPLLLKQLELMLTSGELN
SRNQHCVTLYAKGLTCDADSLGSHGYIYIAIYPTPATTT

Nucleotide

• Length: 360 bp

>AT201704 NZ_CP098723:c1561086-1560940 [Yersinia ruckeri]
AGATAAAAAAAGACCGAATACGAATCCTATATTCGGTCCAGGGAAATGGCTCTTGGGATAGAGCCGTGCGCTAAAAGTTG
GCATTTCATGCAGGCTTATTAAGCCGTACCACTTAAGCGTAGTAGACGACCCACATTTTACCAATTT