Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1821155..1821298 Replicon chromosome
Accession NZ_CP074154
Organism Enterobacter asburiae strain JBIWA007

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1821190..1821293 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1821155..1821298 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP18_RS08790 (KGP18_08795) 1817639..1818301 - 663 WP_223537004.1 exodeoxyribonuclease X -
KGP18_RS08795 (KGP18_08800) 1818326..1818976 - 651 WP_223537006.1 carbon-nitrogen hydrolase family protein -
KGP18_RS08800 (KGP18_08805) 1819087..1819317 - 231 WP_013096102.1 DNA polymerase III subunit theta -
KGP18_RS08805 (KGP18_08810) 1819454..1819825 + 372 WP_223537009.1 CopC domain-containing protein YobA -
KGP18_RS08810 (KGP18_08815) 1819827..1820696 + 870 WP_063439340.1 copper homeostasis membrane protein CopD -
KGP18_RS08815 (KGP18_08820) 1820713..1821051 + 339 WP_045404471.1 YebY family protein -
- 1821155..1821298 - 144 - - Antitoxin
- 1821190..1821293 + 104 - - Toxin
KGP18_RS08820 (KGP18_08825) 1821478..1822536 - 1059 WP_223537011.1 ParA family protein -
KGP18_RS08825 (KGP18_08830) 1822656..1823732 - 1077 WP_223537013.1 phage integrase Arm DNA-binding domain-containing protein -
KGP18_RS08830 (KGP18_08835) 1823710..1823961 - 252 WP_083581992.1 excisionase -
KGP18_RS08835 (KGP18_08840) 1824220..1824522 - 303 WP_223537016.1 hypothetical protein -
KGP18_RS08840 (KGP18_08845) 1824736..1825272 - 537 WP_223537019.1 phage N-6-adenine-methyltransferase -
KGP18_RS08845 (KGP18_08850) 1825265..1825972 - 708 WP_223537022.1 polymer-forming cytoskeletal protein -
KGP18_RS08850 (KGP18_08855) 1825984..1826205 - 222 WP_223537025.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1814849..1858955 44106


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T201682 NZ_CP074154:1821190-1821293 [Enterobacter asburiae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT201682 NZ_CP074154:c1821298-1821155 [Enterobacter asburiae]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References