Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 306051..306467 Replicon chromosome
Accession NZ_CP074149
Organism Enterobacter sp. JBIWA008

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag KGP24_RS24735 Protein ID WP_282454308.1
Coordinates 306267..306467 (-) Length 67 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag KGP24_RS01445 Protein ID WP_223562136.1
Coordinates 306051..306266 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP24_RS01440 (KGP24_01440) 304423..306054 + 1632 WP_223562135.1 Na/Pi cotransporter family protein -
KGP24_RS01445 (KGP24_01445) 306051..306266 - 216 WP_223562136.1 putative addiction module antidote protein Antitoxin
KGP24_RS24735 306267..306467 - 201 WP_282454308.1 hypothetical protein Toxin
KGP24_RS01450 (KGP24_01450) 306587..307459 + 873 WP_223562137.1 23S rRNA pseudouridine(2604) synthase RluF -
KGP24_RS01455 (KGP24_01455) 307460..307732 - 273 WP_223562138.1 DUF3811 domain-containing protein -
KGP24_RS01460 (KGP24_01460) 307783..308727 - 945 WP_223562139.1 ketopantoate/pantoate/pantothenate transporter PanS -
KGP24_RS01465 (KGP24_01465) 308821..310170 - 1350 WP_223562140.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Uncharacterized protein HI1420

(13-65)


Sequences

Toxin        


Download         Length: 67 a.a.        Molecular weight: 7292.49 Da        Isoelectric Point: 8.2677

>T201663 WP_282454308.1 NZ_CP074149:c306467-306267 [Enterobacter sp. JBIWA008]
IYPCANSLTIIASRLFRLANGLAGDRIYFKDQGNCIIVLLCGGDKSSQARDILMAKMLSNVSQWQE

Download         Length: 201 bp

>T201663 NZ_CP098710:1829063-1829521 [Yersinia ruckeri]
GTGATGCTCTACCGGATAGTTCACAACCGTTACCTGGCAACGGCCTGGACCGGATATGGCGCAGAAACCTATGGTGGCCG
CTGGAATCATAAAGGCCATGCGGCGATTTATCTGGCCAGTAGCGTTTCTCTGGCGATGCTCGAAACACTGGTGCATGTAG
AAGATAGCGCGACGCTGAACGATTTTAATCTATTTCAGATAACCATTCCCGATAATGCAATTATGGTACTGCAACAGCAA
GATTGGCCACGTGGATGGCGAGATGACCCCACCCCCGTGGCTACCATGGACATCGGCACCGAATGGATTGGTTCAGTATC
ATCTGTCGGTCTGCTGGTACCATCCACGTTAGTCCCTTTGGAAAGAAATATGCTGGTGAATCCTAAACACCGCGATTTCG
CCTCGTGCCTGAAAAGCATCAATCCACTGACGTTCAGTTTTGATCCTCGTCTAAAGTAA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 7577.76 Da        Isoelectric Point: 10.6291

>AT201663 WP_223562136.1 NZ_CP074149:c306266-306051 [Enterobacter sp. JBIWA008]
MSMHKLTSYDPANALGVIARSKGISTISQQTGLSREQLYRSFSDKGNPTLKTTLAVMKALGLGLTIKHAGD

Download         Length: 216 bp

>AT201663 NZ_CP098710:1828603-1829049 [Yersinia ruckeri]
ATGAGAACTTATCACCCAAGCCCGATGGCCAAAGTCAGCGCACTATGGCGTGAGATTGGTCTACCCGCCAGTCGTGGCAC
CGCTTTGGTGGACAGCATAAAACTGGGATTTACTGTGGATGTGATCGACACTATACATTTATGGGCTGATATGCCTAAAT
CTGAAATATTACGCGCTACGGGCATTCCGAGCCGCAGTCTGACGCGCCGTCGTACCCATGATGGGCGTTTTACCCCGGAA
GAAAGCGAACGTATTGCACGGTTTGTCCGGGTTATGGATGCGGCGGTAGATTTGTTCGGTGGTGACCGCACCAAAGCAAC
CGCATGGATGTCGATGCCGGTCAAAGGGCTGGGTAATCGAACGCCCGATTCACTGCTGGAAACCGAAACCGGTGCGTTGG
AAATCTGCGACCTGATTGGTCGTCTCGAACATGGGGTCTTTTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References