Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 5173802..5174324 Replicon chromosome
Accession NZ_CP074147
Organism Serratia sp. JSRIV001

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KGP17_RS23970 Protein ID WP_223498519.1
Coordinates 5174043..5174324 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8I0CUG0
Locus tag KGP17_RS23965 Protein ID WP_071682601.1
Coordinates 5173802..5174053 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP17_RS23940 (KGP17_23855) 5169351..5170160 - 810 WP_115160005.1 SDR family oxidoreductase -
KGP17_RS23945 (KGP17_23860) 5170157..5170813 - 657 WP_021180630.1 iron-containing redox enzyme family protein -
KGP17_RS23950 (KGP17_23865) 5170810..5172249 - 1440 WP_094983167.1 AMP-dependent synthetase/ligase -
KGP17_RS23955 (KGP17_23870) 5172246..5172890 - 645 WP_223498517.1 thermostable hemolysin -
KGP17_RS23960 (KGP17_23875) 5173084..5173737 + 654 WP_223498518.1 Qnr family pentapeptide repeat protein -
KGP17_RS23965 (KGP17_23880) 5173802..5174053 + 252 WP_071682601.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KGP17_RS23970 (KGP17_23885) 5174043..5174324 + 282 WP_223498519.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KGP17_RS23975 (KGP17_23890) 5174493..5175128 + 636 WP_115160006.1 glutathione transferase -
KGP17_RS23980 (KGP17_23895) 5175239..5176693 - 1455 WP_021180637.1 NAD-dependent succinate-semialdehyde dehydrogenase -
KGP17_RS23985 (KGP17_23900) 5176706..5177971 - 1266 WP_166733462.1 4-aminobutyrate--2-oxoglutarate transaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11003.94 Da        Isoelectric Point: 10.6704

>T201658 WP_223498519.1 NZ_CP074147:5174043-5174324 [Serratia sp. JSRIV001]
MIYKLKFEKRALKEWEKLGYPVREQLKKKLAERLENPHVPASRLSGRPNRYKIKLRSSGYRLVYEVRDNEIVLLVIAVGK
RAGEEVYFAADKR

Download         Length: 282 bp

>T201658 NZ_CP098708:c58634-58344 [Yersinia ruckeri]
ATGATTAAGTCTTTTCGGGATAAAAACCTAGAACTGTTCTATATGGAAAGTAAACGAGATCGCGCGATACCGGCAACAAT
AGAGCGCCAGTTAGCGAAGAAGCTTGATATGTTGGCCGCCGCACATAATGAGCGAGATTTGTTTATTCCAACCAGTAATT
ACTACAAGCGTCTCTCAGGGCAGTTTGATGGCTGGTCAAGTATGAGAGTCAATATTCAATGGCGGTTAATGTTTCAATGG
AAAGACGGATATGCTGAAAGCATCTACCTCGATCCTCATCAAGACACCTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9242.38 Da        Isoelectric Point: 3.8427

>AT201658 WP_071682601.1 NZ_CP074147:5173802-5174053 [Serratia sp. JSRIV001]
MAFQILTTIAASITDLKKNPMGTVADGEGEAVAILNRNEPAFYCVPPELYAYYRELAEDAELNRIADERMEDAEFVSVNL
NDL

Download         Length: 252 bp

>AT201658 NZ_CP098708:c58332-58003 [Yersinia ruckeri]
ATGCTTGATACCACTACTCGCGAACCTACTACGGTAGGCGAAATTTTGCAGGAAGAATTTTTAACCCCATTAGCCATTGG
GCAGGAAGAACTGGCCGATATTATGGGCGTGACTCGCGCAACGGTTAACCGTTTGTGCAAAGGCCGTCGTCGTCTGACTG
TAGAGGAAGCGACGCTGTTTTCTGAGTTGTTTGAGACGACGCCCGAATTTTGGTTGAACCTCCAAGCCGCTCATGACCGT
TGGGAAGCACGAGAAGCGCTTCAAAAACATAAGCGACCCCCAATGCGTCCTATCATGGAAATGTTGGGACGGCGTATCTC
ACACGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References