201652

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4381478..4382141 Replicon chromosome
Accession NZ_CP074147
Organism Serratia sp. JSRIV001

Toxin (Protein)


Gene name tad Uniprot ID A0A8H9YC74
Locus tag KGP17_RS20285 Protein ID WP_071683941.1
Coordinates 4381478..4381822 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag KGP17_RS20290 Protein ID WP_024484273.1
Coordinates 4381824..4382141 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP17_RS20265 (KGP17_20190) 4377664..4378170 - 507 WP_024484269.1 tRNA adenosine(34) deaminase TadA -
KGP17_RS20270 (KGP17_20195) 4378499..4379650 + 1152 WP_059201549.1 L-threonine dehydrogenase -
KGP17_RS20275 (KGP17_20200) 4379690..4380337 - 648 WP_021178894.1 phosphatidylglycerophosphatase C -
KGP17_RS20280 (KGP17_20205) 4380568..4381377 + 810 WP_094982605.1 MurR/RpiR family transcriptional regulator -
KGP17_RS20285 (KGP17_20210) 4381478..4381822 + 345 WP_071683941.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KGP17_RS20290 (KGP17_20215) 4381824..4382141 + 318 WP_024484273.1 helix-turn-helix transcriptional regulator Antitoxin
KGP17_RS20295 (KGP17_20220) 4382219..4382479 + 261 WP_071683942.1 YfhL family 4Fe-4S dicluster ferredoxin -
KGP17_RS20300 (KGP17_20225) 4382631..4383011 - 381 WP_059201551.1 holo-ACP synthase -
KGP17_RS20305 (KGP17_20230) 4383011..4383742 - 732 WP_071683945.1 pyridoxine 5'-phosphate synthase -
KGP17_RS20310 (KGP17_20235) 4383817..4384548 - 732 WP_021178899.1 DNA repair protein RecO -
KGP17_RS20315 (KGP17_20240) 4384557..4385465 - 909 WP_094982606.1 GTPase Era -
KGP17_RS20320 (KGP17_20245) 4385462..4386142 - 681 WP_021178901.1 ribonuclease III -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12507.28 Da        Isoelectric Point: 9.6410

>T201652 WP_071683941.1 NZ_CP074147:4381478-4381822 [Serratia sp. JSRIV001]
MKPLYWVGSSKKDLQSLPEEVQDVFGYALHLAQAGGKHSQTKPLRGFGGAGVLEVVEDFLTDTYRAVYTVKFGDAVYVLH
AFQKKSSAGIATPKPDMDKIRERLKAAENHARGA

Download         Length: 345 bp

>T201652 NZ_CP098706:c954439-954236 [Yersinia ruckeri]
ATGACCAAAACTGACTACCTAATGCGTTTAAGAAAATGCACAACAATTGACACACTAGAGCGTGTTATTGAAAAAAATAA
GTATGAGCTATCTGATGATGAACTAGAATTATTCTATTCTGCTGCGGATCATCGTCTAGCTGAACTTACCATGAATAAGT
TATACGATAAAATTCCTGCAACTGTCTGGCAACATGTGAAGTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11403.22 Da        Isoelectric Point: 10.2057

>AT201652 WP_024484273.1 NZ_CP074147:4381824-4382141 [Serratia sp. JSRIV001]
MSQDIEVSSGNVYADIGSDGAEEMQVKAQLASTIGDIIKSRRLTQEQAAKLLGMTQPKLSNLLRGQFRGISEAKMLECLT
RLGRDVQIVVGKPRRTPGSLKVVFA

Download         Length: 318 bp

>AT201652 NZ_CP098706:c954859-954491 [Yersinia ruckeri]
ATGGATGAGTACTCACCTAAGCGACATGATATTGCTCAGTTGAAATTCTTATGTGAGAATTTGTATGATGAAGGTATCGC
CACATTGGGCGATAGCCACCACGGCTGGGTTAATGATCCAACCTCCGCGGTAAATCTCCAACTGAATGATTTAATCGAAC
ACATAGCTTCATTTGTGATGAGTTTTAAAATAAAATACGCAGACGAAATCGATCTCTGCGAGTTGGTGGAGGAATATCTA
GACGATACATATACCTTGTTCAGCAGTTACGGAATCAATGATCCTGATTTACGCCGCTGGCAGAAAACAAAAGACCGATT
ATTCAGACTATTTTCAGGGGAATACCTATGTGCCCTGATGAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References