201628

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 5118864..5119419 Replicon chromosome
Accession NZ_CP074143
Organism Serratia sp. JSRIV002

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KGP26_RS30275 Protein ID WP_245398320.1
Coordinates 5119285..5119419 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KGP26_RS24085 Protein ID WP_223498456.1
Coordinates 5118864..5119145 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP26_RS24040 (KGP26_23955) 5114161..5114613 + 453 WP_223498447.1 hypothetical protein -
KGP26_RS24045 (KGP26_23960) 5114610..5115062 + 453 WP_223498448.1 IrmA family protein -
KGP26_RS24050 (KGP26_23965) 5115208..5115642 + 435 WP_223498449.1 antirestriction protein -
KGP26_RS24055 (KGP26_23970) 5115660..5116148 + 489 WP_223498450.1 DNA repair protein RadC -
KGP26_RS24060 (KGP26_23975) 5116142..5116462 + 321 WP_223498451.1 DUF5983 family protein -
KGP26_RS24065 (KGP26_23980) 5116526..5117008 + 483 WP_223498452.1 hypothetical protein -
KGP26_RS24070 (KGP26_23985) 5117021..5117356 + 336 WP_223498453.1 TA system toxin CbtA family protein -
KGP26_RS24075 (KGP26_23990) 5117434..5117811 + 378 WP_223498454.1 type IV toxin-antitoxin system YeeU family antitoxin -
KGP26_RS24080 (KGP26_23995) 5117890..5118747 + 858 WP_223498455.1 DUF4942 domain-containing protein -
KGP26_RS24085 (KGP26_24000) 5118864..5119145 + 282 WP_223498456.1 ribbon-helix-helix domain-containing protein Antitoxin
KGP26_RS30275 5119285..5119419 + 135 WP_245398320.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KGP26_RS24095 (KGP26_24010) 5119710..5120822 - 1113 WP_094981420.1 M20 family metallopeptidase -
KGP26_RS24100 (KGP26_24015) 5120919..5121380 - 462 WP_037434993.1 YjiG family protein -
KGP26_RS24105 (KGP26_24020) 5121397..5122131 - 735 WP_094981419.1 nucleoside recognition domain-containing protein -
KGP26_RS24110 (KGP26_24025) 5122663..5123466 - 804 WP_223664669.1 histidine phosphatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-43)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 5538.39 Da        Isoelectric Point: 10.5247

>T201628 WP_245398320.1 NZ_CP074143:5119285-5119419 [Serratia sp. JSRIV002]
MRPALARYEPREVRRLNIGNYEIHYELRVNALYILRVWHTRENR

Download         Length: 135 bp

>T201628 NZ_CP098697:1878252-1878710 [Yersinia ruckeri]
GTGATGCTCTACCGGATAGTTCACAACCGTTACCTGGCAACGGCCTGGACCGGATATGGCGCAGAAACCTATGGTGGCCG
CTGGAATCATAAAGGCCATGCGGCGATTTATCTGGCCAGTAGCGTTTCTCTGGCGATGCTCGAAACACTGGTGCATGTAG
AAGATAGCGCGACGCTGAACGATTTTAATCTATTTCAGATAACCATTCCCGATAATGCAATTATGGTACTGCAACAGCAA
GATTGGCCACGTGGATGGCGAGATGACCCCACCCCCGTGGCCACCATGGACATCGGCACCGAATGGATTGGTTCAGTATC
ATCTGTCGGTCTGCTGGTACCATCCACGTTAGTCCCTTTGGAAAGAAATATGCTGGTGAATCCTAAACACCGCGATTTCG
CCTCGTGCCTGAAAAGCATCAATCCACTGACGTTCAGTTTTGATCCTCGTCTAAAGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10503.87 Da        Isoelectric Point: 4.8000

>AT201628 WP_223498456.1 NZ_CP074143:5118864-5119145 [Serratia sp. JSRIV002]
MGQSPTRVITAHVPAEMVEKFDELAANYDRSRGWIVKQVLAANIEQEENHHQMILRGLADVDESRVVEQTDVLKWINSLN
IDTPLPVPQSGQK

Download         Length: 282 bp

>AT201628 NZ_CP098697:1877792-1878238 [Yersinia ruckeri]
ATGAGAACTTATCACCCAAGCCCGATGGCCAAAGTCAGCGCACTATGGCGTGAGATTGGTCTACCCGCCAGTCGTGGCAC
CGCTTTGGTGGACAGCATAAAACTGGGATTTACTGTGGATGTGATCGACACTATACATTTATGGGCTGATATGCCTAAAT
CTGAAATATTACGCGCTACGGGCATTCCGAGCCGCAGTCTGACGCGCCGTCGTACCCATGATGGGCGTTTTACCCCGGAA
GAAAGCGAACGTATTGCACGGTTTGTCCGGGTTATGGATGCGGCGGTAGATTTGTTCGGTGGTGACCGCACCAAAGCAAC
CGCATGGATGTCGATGCCGGTCAAAGGGCTGGGTAATCGAACGCCCGATTCACTGCTGGAAACCGAAACCGGTGCGTTGG
AAATCTGCGACCTGATTGGTCGTCTCGAACATGGGGTCTTTTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References