201615

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3512775..3512872 Replicon chromosome
Accession NZ_CP074143
Organism Serratia sp. JSRIV002

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3512777..3512872 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3512775..3512863 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP26_RS16475 (KGP26_16415) 3507946..3508488 - 543 WP_059201044.1 hypothetical protein -
KGP26_RS16480 (KGP26_16420) 3508916..3510187 - 1272 WP_021806748.1 translesion error-prone DNA polymerase V subunit UmuC -
KGP26_RS16485 (KGP26_16425) 3510187..3510609 - 423 WP_021806749.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
KGP26_RS16490 (KGP26_16430) 3510829..3511314 - 486 WP_223499939.1 anti-virulence regulator CigR family protein -
KGP26_RS16495 (KGP26_16435) 3511625..3512497 - 873 WP_223535717.1 excinuclease Cho -
- 3512775..3512863 + 89 - - Antitoxin
- 3512777..3512872 - 96 - - Toxin
KGP26_RS16500 (KGP26_16440) 3513013..3513354 - 342 WP_021806756.1 YebY family protein -
KGP26_RS16505 (KGP26_16445) 3513424..3514305 - 882 WP_218519230.1 copper homeostasis membrane protein CopD -
KGP26_RS16510 (KGP26_16450) 3514309..3514692 - 384 WP_024485865.1 CopC domain-containing protein YobA -
KGP26_RS16515 (KGP26_16455) 3515015..3515533 - 519 WP_021806759.1 non-heme ferritin -
KGP26_RS16520 (KGP26_16460) 3515922..3516152 + 231 WP_021181054.1 DNA polymerase III subunit theta -
KGP26_RS16525 (KGP26_16465) 3516160..3517385 - 1226 Protein_3236 IS481 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - chuW / chuY 3480765..3527503 46738
- flank IS/Tn - - 3516231..3517373 1142


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 96 bp

>T201615 NZ_CP074143:c3512872-3512777 [Serratia sp. JSRIV002]
AACAAACCTTGCATAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCCTTTCCCTAGACCGAGTATAGGAATCG
TACTCGGTCTTTTTTT

Antitoxin


Download         Length: 89 bp

>AT201615 NZ_CP074143:3512775-3512863 [Serratia sp. JSRIV002]
ATAAAAAAAGACCGAGTACGATTCCTATACTCGGTCTAGGGAAAGGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTTATGCA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References