201613

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 1520721..1521533 Replicon chromosome
Accession NZ_CP074143
Organism Serratia sp. JSRIV002

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag KGP26_RS06920 Protein ID WP_223665188.1
Coordinates 1520721..1521104 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag KGP26_RS06925 Protein ID WP_223665189.1
Coordinates 1521165..1521533 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP26_RS06880 (KGP26_06870) 1516614..1517327 + 714 WP_094981159.1 MgtC/SapB family protein -
KGP26_RS06885 (KGP26_06875) 1517398..1517610 - 213 WP_021180059.1 ribosome-associated protein YbcJ -
KGP26_RS06890 (KGP26_06880) 1517622..1518488 - 867 WP_223665185.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD -
KGP26_RS06895 (KGP26_06885) 1518717..1518929 + 213 WP_209523136.1 hypothetical protein -
KGP26_RS06900 (KGP26_06890) 1518926..1519237 + 312 WP_209528426.1 hypothetical protein -
KGP26_RS06910 (KGP26_06900) 1519557..1520408 - 852 WP_223665186.1 DUF4942 domain-containing protein -
KGP26_RS06915 (KGP26_06905) 1520503..1520724 - 222 WP_223665187.1 DUF5983 family protein -
KGP26_RS06920 (KGP26_06910) 1520721..1521104 - 384 WP_223665188.1 TA system toxin CbtA family protein Toxin
KGP26_RS06925 (KGP26_06915) 1521165..1521533 - 369 WP_223665189.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
KGP26_RS06930 (KGP26_06920) 1521626..1521946 - 321 WP_223665190.1 DUF5983 family protein -
KGP26_RS06935 (KGP26_06925) 1521957..1522436 - 480 WP_223665191.1 DNA repair protein RadC -
KGP26_RS06940 (KGP26_06930) 1522456..1522902 - 447 WP_223665192.1 antirestriction protein -
KGP26_RS06945 (KGP26_06935) 1523138..1523605 - 468 WP_223665193.1 hypothetical protein -
KGP26_RS06950 1523707..1523853 - 147 Protein_1345 DUF4339 domain-containing protein -
KGP26_RS06955 (KGP26_06940) 1523977..1524609 - 633 WP_223665194.1 hypothetical protein -
KGP26_RS06960 (KGP26_06945) 1524615..1525316 - 702 WP_050082059.1 WYL domain-containing protein -
KGP26_RS06965 (KGP26_06950) 1525529..1526404 - 876 WP_223665195.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14181.32 Da        Isoelectric Point: 9.9985

>T201613 WP_223665188.1 NZ_CP074143:c1521104-1520721 [Serratia sp. JSRIV002]
MQTVSVTPKRAAPSCPSPIAIWQVLLTHLLQQHYGLALEDTAFSHEGVIQEHLNAGISLADALNFIVEKYELVRIDRTGF
SIREQSPFITPIDLLRARQATGLMKRRGYKAITHITNGKNQRQGAHP

Download         Length: 384 bp

>T201613 NZ_CP098694:2634989-2635192 [Yersinia ruckeri]
ATGACCAAAACTGACTACCTAATGCGTTTAAGAAAATGCACAACAATTGACACACTAGAGCGTGTTATTGAAAAAAATAA
GTATGAGCTATCTGATGATGAACTAGAATTATTCTATTCTGCTGCGGATCATCGTCTAGCTGAACTTACCATGAATAAGT
TATACGATAAAATTCCTGCAACTGTCTGGCAACATGTGAAGTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13450.26 Da        Isoelectric Point: 5.9492

>AT201613 WP_223665189.1 NZ_CP074143:c1521533-1521165 [Serratia sp. JSRIV002]
MTDSKPDTPSQGADITPPAWGLKRIITPQFGARLVQQGHQLHYLADRADIVGKFSDAELRHLDQVFPLWLQQLESMLMSA
ELNPRQQHCVTLHASGLTLEADTLGSCGYVYISIYPTSATTA

Download         Length: 369 bp

>AT201613 NZ_CP098694:2634569-2634937 [Yersinia ruckeri]
ATGGATGAGTACTCACCTAAGCGACATGATATTGCTCAGTTGAAATTCTTATGTGAGAATTTGTATGATGAAGGTATCGC
CACATTGGGCGATAGCCACCACGGCTGGGTTAATGATCCAACCTCCGCGGTAAATCTCCAACTGAATGATTTAATCGAAC
ACATAGCTTCATTTGTGATGAGTTTTAAAATAAAATACGCAGACGAAATCGATCTCTGCGAGTTGGTGGAGGAATATCTA
GACGATACATATACCTTGTTCAGCAGTTACGGAATCAATGATCCTGATTTACGCCGCTGGCAGAAAACAAAAGACCGATT
ATTCAGACTATTTTCAGGGGAATACCTATGTGCCCTGATGAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References