Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 132267..132963 Replicon chromosome
Accession NZ_CP074140
Organism Serratia sp. JSRIV004

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag KGP21_RS00520 Protein ID WP_223536849.1
Coordinates 132267..132602 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag KGP21_RS00525 Protein ID WP_223536852.1
Coordinates 132679..132963 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP21_RS00490 (KGP21_00490) 128388..128798 + 411 WP_223536836.1 hypothetical protein -
KGP21_RS00495 (KGP21_00495) 128864..129805 + 942 WP_223536837.1 hypothetical protein -
KGP21_RS29610 129941..130066 + 126 WP_256461389.1 hypothetical protein -
KGP21_RS00500 (KGP21_00500) 130441..130887 + 447 WP_223536838.1 antirestriction protein -
KGP21_RS00505 (KGP21_00505) 130905..131393 + 489 WP_223536841.1 DNA repair protein RadC -
KGP21_RS00510 (KGP21_00510) 131387..131707 + 321 WP_223536844.1 DUF5983 family protein -
KGP21_RS00515 (KGP21_00515) 131771..132253 + 483 WP_223536847.1 hypothetical protein -
KGP21_RS00520 (KGP21_00520) 132267..132602 + 336 WP_223536849.1 TA system toxin CbtA family protein Toxin
KGP21_RS00525 (KGP21_00525) 132679..132963 + 285 WP_223536852.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
KGP21_RS00530 (KGP21_00530) 133053..133910 + 858 WP_223536855.1 DUF4942 domain-containing protein -
KGP21_RS00535 (KGP21_00535) 134336..134601 - 266 Protein_106 transposase -
KGP21_RS00540 (KGP21_00540) 134883..136046 - 1164 WP_223536857.1 DUF4238 domain-containing protein -
KGP21_RS00545 (KGP21_00545) 136523..137407 - 885 WP_223536860.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 122727..180611 57884


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(15-104)

Antitoxin

Antitoxin CbeA

(14-90)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12485.26 Da        Isoelectric Point: 5.0858

>T201574 WP_223536849.1 NZ_CP074140:132267-132602 [Serratia sp. JSRIV004]
MKAIDKIPHTAPNANQALAEYEQLLTWLLNHCYGLELNDTPYHDPQAIAQQIEYGMTVRETINELVEKFDLVRIDRPGFS
LLAQDPTLSGGDMLLARSALGLRNPVNRRLA

Download         Length: 336 bp

>T201574 NZ_CP098547:101-379 [Neisseria gonorrhoeae]
ATGTACGCGATTTCTTTTGATTTGGTGGTTGCCGATACCGCTCAAAACCATCCGAAAGGCATTTCCCAAGCCTACGCGGA
TATTGGATACACCCTGCGGAAATTCGGCTTTACCCGCATTCAGGGAAGTTTGTACACCTGCCAAAACGAAGATATGGCTA
ACCTGTTTTCAGCCATCAACGAGCTAAAAGCTCTGCCTTGGTTTCCGTCTTCTGTCCGCGATATTCGGGCGTTCCGCATT
GAGCAGTGGTCTGATTTCACAAGTCTTGTGAAGTCTTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10424.05 Da        Isoelectric Point: 6.7069

>AT201574 WP_223536852.1 NZ_CP074140:132679-132963 [Serratia sp. JSRIV004]
MKNLEPDIPPTAPVWGLQCAITPRLGARLVQQGRHLHFLADRAGLIGTFTPEAIKALDVAFPVLIEQLENYLRSGELDPR
RQHCVTVQLSPSTE

Download         Length: 285 bp

>AT201574 NZ_CP098547:4123-101 [Neisseria gonorrhoeae]

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References