Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 5011911..5012433 Replicon chromosome
Accession NZ_CP074137
Organism Serratia sp. JSRIV006

Toxin (Protein)


Gene name relE Uniprot ID A0A0U4JRE1
Locus tag KGP16_RS23130 Protein ID WP_021806920.1
Coordinates 5012152..5012433 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0U4HY11
Locus tag KGP16_RS23125 Protein ID WP_021806919.1
Coordinates 5011911..5012162 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10991.89 Da        Isoelectric Point: 10.6704

>T201571 WP_021806920.1 NZ_CP074137:5012152-5012433 [Serratia sp. JSRIV006]
MTYKLKFEKRALKEWEKLGYPVREQLKKKLAERLENPHVPASRLSGRPNRYKIKLRSSGYRLVYEVRDNEIVLLVIAVGK
RAGEEVYFAADKR

Download         Length: 282 bp

>T201571 NZ_CP098545:36-314 [Neisseria gonorrhoeae]
ATGTACGCGATTTCTTTTGATTTGGTGGTTGCCGATACCGCTCAAAACCATCCGAAAGGCATTTCCCAAGCCTACGCGGA
TATTGGATACACCCTGCGGAAATTCGGCTTTACCCGCATTCAGGGAAGTTTGTACACCTGCCAAAACGAAGATATGGCTA
ACCTGTTTTCAGCCATCAACGAGCTAAAAGCTCTGCCTTGGTTTCCGTCTTCTGTCCGCGATATTCGGGCGTTCCGCATT
GAGCAGTGGTCTGATTTCACAAGTCTTGTGAAGTCTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9243.37 Da        Isoelectric Point: 3.7947

>AT201571 WP_021806919.1 NZ_CP074137:5011911-5012162 [Serratia sp. JSRIV006]
MAFQILTTIAASITDLKKNPMGTVADGEGEAVAILNRNEPAFYCVPPELYAYYRELAEDAELNRIADERMEDAEFVSVDL
NDL

Download         Length: 252 bp

>AT201571 NZ_CP098545:4004-36 [Neisseria gonorrhoeae]

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0U4JRE1

Antitoxin

Source ID Structure
AlphaFold DB A0A0U4HY11

References