Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 455437..455903 Replicon chromosome
Accession NZ_CP074137
Organism Serratia sp. JSRIV006

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KGP16_RS02000 Protein ID WP_223500736.1
Coordinates 455437..455712 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KGP16_RS02005 Protein ID WP_223500737.1
Coordinates 455712..455903 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGP16_RS01985 (KGP16_01980) 450570..452045 + 1476 WP_223500731.1 TIGR03752 family integrating conjugative element protein -
KGP16_RS01990 (KGP16_01985) 452076..452486 + 411 WP_223500733.1 TIGR03751 family conjugal transfer lipoprotein -
KGP16_RS01995 (KGP16_01990) 452540..455284 + 2745 WP_223501485.1 conjugative transfer ATPase -
KGP16_RS02000 (KGP16_01995) 455437..455712 - 276 WP_223500736.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KGP16_RS02005 (KGP16_02000) 455712..455903 - 192 WP_223500737.1 stability determinant Antitoxin
KGP16_RS02010 (KGP16_02005) 456075..456479 + 405 WP_223500738.1 TIGR03757 family integrating conjugative element protein -
KGP16_RS02015 (KGP16_02010) 456533..457459 + 927 WP_223501486.1 TIGR03756 family integrating conjugative element protein -
KGP16_RS02020 (KGP16_02015) 457477..458925 + 1449 WP_223500739.1 integrating conjugative element protein -
KGP16_RS02025 (KGP16_02020) 458939..459310 + 372 WP_223500740.1 hypothetical protein -
KGP16_RS02030 (KGP16_02025) 459310..460851 + 1542 WP_223501488.1 conjugal transfer protein TraG N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 417603..474212 56609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10655.20 Da        Isoelectric Point: 5.0747

>T201548 WP_223500736.1 NZ_CP074137:c455712-455437 [Serratia sp. JSRIV006]
MLTVKWTDEARNELYALIRFIAEQNPFAAESLMQRIEDSVLPATEHPYLFRPGRIPGTREIVAHPNYIVVYQVKDDFLEV
LDVLHARQQYP

Download         Length: 276 bp

>T201548 NZ_CP098511:1366294-1366596 [Aquimarina sp. ERC-38]
ATGTTTTTTATTGAGAAAACAAAAGAGTTTAATAAATGGTTTAGAAAATTAAAAGACTCAAAAGCTAAAACAAAAATTCT
TTATAGAATTCAAAGATTAGAAAATGACGAACATTTTGGAGATTGCAAACCTGTAGGTGATGGAATTAAAGAAATTAGAA
TAAATTTTGCTAAAGAATATCGTATTTATTTCAAGGAGAAAAATGGGAGAATAATTATTTTACTAATAGGTGGAGATAAA
TCAACTCAACAAAAAGATATTAAGAAAGCAAAAGAAATTTGGAATAAATTAAATAATTTATAA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7262.31 Da        Isoelectric Point: 9.8642

>AT201548 WP_223500737.1 NZ_CP074137:c455903-455712 [Serratia sp. JSRIV006]
MTIKLSPIVSEFETQEQADSYDRWFRAKVEAAMNSTKPRIPHDEVMAGARKIIEEAKARRKQA

Download         Length: 192 bp

>AT201548 NZ_CP098511:1366598-1366882 [Aquimarina sp. ERC-38]
ATGGAAACTTCAAAATTTGATATTGCAGATTATCTAGACAGTAAAGAAATGATTGTAGAATATCTTAATACTGTTCTGGA
AGAAGGTAATGATGCTGATATGGTTGTTGCTATTGGTCATGTTGCAAAAGCAATTGGAATGTCGAAAATTGCGGAGGAAA
CTGGGTTGAGTAGACCTAGTTTATACAAAGCTTTATCGGATGGGGCTAAACCTCAATTTGCAACTATTGTAAAAGTGTTA
AAAGCTATTGGCGGACAGATTCAAATAAATCCTTTGTCAGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References