Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2069545..2069690 Replicon chromosome
Accession NZ_CP074116
Organism Klebsiella pneumoniae subsp. pneumoniae strain kpn-hnqyy

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2069581..2069683 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2069545..2069690 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGB32_RS10195 (KGB32_10195) 2064675..2066735 + 2061 WP_004151449.1 oligopeptidase B -
KGB32_RS10200 (KGB32_10200) 2066739..2067398 - 660 WP_002911407.1 exodeoxyribonuclease X -
KGB32_RS10205 (KGB32_10205) 2067477..2067707 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KGB32_RS10210 (KGB32_10210) 2067820..2068194 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KGB32_RS10215 (KGB32_10215) 2068198..2069067 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
KGB32_RS10220 (KGB32_10220) 2069084..2069422 + 339 WP_002911404.1 YebY family protein -
- 2069545..2069690 - 146 - - Antitoxin
- 2069581..2069683 + 103 - - Toxin
KGB32_RS10225 (KGB32_10225) 2070058..2070201 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KGB32_RS10230 (KGB32_10230) 2070306..2071274 - 969 WP_004151446.1 VirK/YbjX family protein -
KGB32_RS10235 (KGB32_10235) 2071431..2072084 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KGB32_RS10240 (KGB32_10240) 2072081..2072272 - 192 WP_002911395.1 YebW family protein -
KGB32_RS10245 (KGB32_10245) 2072370..2072609 - 240 WP_002911393.1 YebV family protein -
KGB32_RS10250 (KGB32_10250) 2072725..2074158 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T201478 NZ_CP074116:2069581-2069683 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT201478 NZ_CP074116:c2069690-2069545 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References