Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2694337..2695361 Replicon chromosome
Accession NZ_CP074112
Organism Idiomarina loihiensis strain SN11

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag KGF88_RS12920 Protein ID WP_153827349.1
Coordinates 2694789..2695361 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag KGF88_RS12915 Protein ID WP_153827348.1
Coordinates 2694337..2694789 (+) Length 151 a.a.

Genomic Context

KGF88_RS12915KGF88_RS12920KGF88_RS12925KGF88_RS12940KGF88_RS12890KGF88_RS12895KGF88_RS12900KGF88_RS12905KGF88_RS12910KGF88_RS12930KGF88_RS12935
Location: 2694337..2694789 (453 bp)
Type: Antitoxin
Protein ID: WP_153827348.1
Location: 2694789..2695361 (573 bp)
Type: Toxin
Protein ID: WP_153827349.1
Location: 2695552..2697405 (1854 bp)
Type: Others
Protein ID: WP_153827350.1
Location: 2699256..2699546 (291 bp)
Type: Others
Protein ID: WP_153827353.1
Location: 2689494..2689967 (474 bp)
Type: Others
Protein ID: WP_153827292.1
Location: 2690012..2690755 (744 bp)
Type: Others
Protein ID: WP_110077105.1
Location: 2690752..2692251 (1500 bp)
Type: Others
Protein ID: WP_257119941.1
Location: 2692379..2693602 (1224 bp)
Type: Others
Protein ID: WP_153827346.1
Location: 2693657..2694076 (420 bp)
Type: Others
Protein ID: WP_153827347.1
Location: 2697415..2698749 (1335 bp)
Type: Others
Protein ID: WP_153827351.1
Location: 2698736..2698963 (228 bp)
Type: Others
Protein ID: WP_162014647.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KGF88_RS12890 (KGF88_12935)2689494..2689967-474WP_153827292.1HNH endonuclease domain-containing protein-
KGF88_RS12895 (KGF88_12940)2690012..2690755-744WP_110077105.1IS21-like element helper ATPase IstB-
KGF88_RS12900 (KGF88_12945)2690752..2692251-1500WP_257119941.1IS21 family transposase-
KGF88_RS12905 (KGF88_12950)2692379..2693602-1224WP_153827346.1class I SAM-dependent methyltransferase-
KGF88_RS12910 (KGF88_12955)2693657..2694076-420WP_153827347.1secondary thiamine-phosphate synthase enzyme YjbQ-
KGF88_RS12915 (KGF88_12960)2694337..2694789+453WP_153827348.1helix-turn-helix domain-containing proteinAntitoxin
KGF88_RS12920 (KGF88_12965)2694789..2695361+573WP_153827349.1PIN domain-containing proteinToxin
KGF88_RS12925 (KGF88_12970)2695552..2697405+1854WP_153827350.1DUF885 domain-containing protein-
KGF88_RS12930 (KGF88_12975)2697415..2698749-1335WP_153827351.1HipA domain-containing protein-
KGF88_RS12935 (KGF88_12980)2698736..2698963-228WP_162014647.1helix-turn-helix domain-containing protein-
KGF88_RS12940 (KGF88_12985)2699256..2699546+291WP_153827353.1helix-turn-helix transcriptional regulator-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--2690012..2690755743


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-114)

Antitoxin

Helix-turn-helix domain, group 17

(80-127)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21740.93 Da        Isoelectric Point: 6.3773

>T201473 WP_153827349.1 NZ_CP074112:2694789-2695361 [Idiomarina loihiensis]
MSSSYTVIFDACVLYPAPLRSLLMYLALSGEFRARWTNDIHDEWIRNVLANRPDLTREQLENVRNLMDKHVPGAIVQNYH
PLISSISLPDEDDRHVVAAAIQTRAEAIVTFNLKDFPDNQLSQYNLKAIHPDDFITDLMELNIVAVIQAVRHHRASLKNP
PFTATQYLDCLLKQKLPEAVSRLSEFKALF

Download         Length: 573 bp

>T201473 NZ_CP098446:c4021970-4020657 [Proteus mirabilis]
ATGGCGAGTCTTGATGTATATATGAATGAATACTATGTGGGCATCTTTACTAAAAAAAGCTCAGGTGCGCATTCATTCCA
ATATACTGAAGATTGGGTTAATCAACCAGGAAGTCGTCCCATCTCTCTTTCGATGCCATTACAGCTTCAAGAATATCAAG
GAGACTGTGTCTATAATTTCTTTGATAATCTGTTACCTGATAATACTGAAATTAGAAATCGTATTGTGAGTCGCTATAAT
GCGAACTCAAATCAACCCTTTGACCTATTAGCGGCTATCGGTGCAGATACTGTTGGTGCATTAAGGTTACTTCCTAGTGG
CAGTACGCCTGCGGATATCAAAAAAATAGAATATCAAAAACTCAATGATATTGAGCTTGAAAAAATTCTACTAGGATATA
AATCCAATACTCCACTCGGTATGCTTAAAGAATATACTGATTTCAGAATTTCCATCGCTGGAGCACAAGAAAAAACAGCA
TTACTTTTAAAAGATAATCATTGGTGTGTGCCACATAATAACACACCAACTACCCATATTATTAAACTGCCAATTGGTGT
TATTGAAAGTCATTCTTATACAATGGATTTATCCAATAGTGTAGAAAATGAGTATCTTTGTACCTTAATTGCCAAAGAAT
TTGATCTTCCCGTCCCCCACTGCTCTATTATTAAAACAAAAAATGTTAAAGCGCTTGCTGTAGAACGTTTTGATAGAAAA
TATTCATCTGATAAATCGTGGATAATACGTTTACCTCAAGAAGATTTTTGCCAAATTTTAAATATACCTTCTGCGCTAAA
ATATGAAAATGAAGGAGGGCCTGGCATTATCGATATTATGAAATATTTACTTGGCTCATCAAATGCCGATCAAGATCGTT
TTCATTTTATGAAGGCACAAGTGCTATTTTGGCTTTTGGCTGCAACGGATGGACACGCAAAGAATTTTTCTGTTTTTATC
AACCAAGAAGGACGTTTCCATCTCACTCCCCTTTATGACATTATGTCCATCTATCCCAATTTCGGAGGACGAGGACTTAA
TCCACGAGATGCAAAACTTGCTATGGGATTAAAAGCAAGCCGAGGCAAAAAATACGCCATAGAACAAATTTTTCCTCGTC
ATTTCTACCAAACAGCTGAAGCTGTCGGTTTCGATCCTTCATTAATGAGCGATATTCTTCGTTATTTTTATCAAGAAATG
GACGATGTCATACAACGCGTAAAACAGCAATTACCCGAGGATTTTCCTTCTGAGATTAGCAATACAATATTAGATGGAAT
GAAAGCACGCGCTGTTAGATTAGCTAACATTTAG

Antitoxin


Download         Length: 151 a.a.        Molecular weight: 16752.24 Da        Isoelectric Point: 5.7816

>AT201473 WP_153827348.1 NZ_CP074112:2694337-2694789 [Idiomarina loihiensis]
MNTYEQLPTAQESALAKLCSQELAAVIETKLDVQSLSLSSPDGQLKQVEIPVSALRLMVNLLTELGEGNTVKLVPIHAEL
TTQEAADLLNVSRPTVIKLLDDGTVPFHRVGNRRKVRFNDIRQYQNQLEQKRLKALNELSKMDQELGLGY

Download         Length: 453 bp

>AT201473 NZ_CP098446:c4022228-4021971 [Proteus mirabilis]
ATGATCATAATTAATGCCTATCAACTCAGTGTGCATCTAAAAGATGTCCGATTAACAAAAAAACTGTCTCAAAGTAAAGT
CGCCCAAAAAGTAGGGATCCGACAAGATACCGTGTCCAATTTTGAACTTAATCCTAATTCCACCAAACTAGAAACCTTTT
TCAAACTGCTCTCCGCACTAAATTTAGAGATGGAAATTCATCCTAAAGATGCTAAAAATAATTTAGCACACAAAAGTGAA
TGGAAAGAGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References