Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1737457..1737979 Replicon chromosome
Accession NZ_CP074112
Organism Idiomarina loihiensis strain SN11

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag KGF88_RS08350 Protein ID WP_110076039.1
Coordinates 1737716..1737979 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag KGF88_RS08345 Protein ID WP_110076040.1
Coordinates 1737457..1737726 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGF88_RS08305 (KGF88_08330) 1732946..1733443 - 498 WP_153825985.1 hypothetical protein -
KGF88_RS08310 (KGF88_08335) 1733448..1734674 - 1227 WP_153825986.1 ATP-binding protein -
KGF88_RS08315 (KGF88_08340) 1734955..1735272 + 318 WP_153825987.1 quaternary ammonium compound efflux SMR transporter SugE -
KGF88_RS08320 (KGF88_08345) 1735482..1735637 + 156 WP_153825988.1 hypothetical protein -
KGF88_RS08325 (KGF88_08350) 1736145..1736444 - 300 WP_110076043.1 type II toxin-antitoxin system RelE/ParE family toxin -
KGF88_RS08330 (KGF88_08355) 1736441..1736680 - 240 WP_110076042.1 addiction module protein -
KGF88_RS08335 (KGF88_08360) 1736833..1737135 - 303 WP_110076041.1 type II toxin-antitoxin system RelE/ParE family toxin -
KGF88_RS08340 (KGF88_08365) 1737123..1737380 - 258 WP_022990189.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
KGF88_RS08345 (KGF88_08370) 1737457..1737726 - 270 WP_110076040.1 CopG family transcriptional regulator Antitoxin
KGF88_RS08350 (KGF88_08375) 1737716..1737979 - 264 WP_110076039.1 BrnT family toxin Toxin
KGF88_RS08355 (KGF88_08380) 1738109..1738504 - 396 WP_202912491.1 hypothetical protein -
KGF88_RS08360 (KGF88_08385) 1738966..1740465 + 1500 WP_257119919.1 IS21 family transposase -
KGF88_RS08365 (KGF88_08390) 1740462..1741205 + 744 WP_110077105.1 IS21-like element helper ATPase IstB -
KGF88_RS08370 (KGF88_08395) 1741519..1742178 - 660 WP_110076038.1 outer membrane beta-barrel protein -
KGF88_RS08375 (KGF88_08400) 1742321..1742623 - 303 WP_110076037.1 HigA family addiction module antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1740462..1741205 743


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10243.62 Da        Isoelectric Point: 7.4016

>T201470 WP_110076039.1 NZ_CP074112:c1737979-1737716 [Idiomarina loihiensis]
MGIFEFDDAKSQANRHKHGIDFHDAQALWEDQDLLEVRAKSSDEPRYLVIGLIGMKHWSAVITYRGEKIRLISVRRSRKR
EVELYES

Download         Length: 264 bp

>T201470 NZ_CP098446:3177795-3178364 [Proteus mirabilis]
ATGACAAACTATACTGTTTTGCTTGATGCCTGTGTCATGTATCCAGCCCCTCTTAGAAGTTATTTAATGTATCTCGCTAA
TACTGGTTTATTTAGAGCACGTTGGAGTAATCAGATCCATGATGAATGGATCACTAATTTATTAGTCAACAATCCAACAT
TAACAGCTGAGCGACTAATACGAACCAGAGATTTAATGAATGCACATGTTCCTGATTGTTTAGTAGAAGGCTACGAACCG
CTTATTTGTGGTTTAAAGCTACCTGATCCTAATGATCGTCATGTGCTAGCAGCAGCAATAAAAGGGCAGGCTCAAGCTAT
AATTACATTTAACTTAAAAGATTTTCCGCAAAAATACCTTAATTCTTTTGATATTTCAGCTATCCATCCTGATGAATTTT
TGAGTGACATGTTTGAATTAAATCCTAGTAGCTGTATTAAAGCGGCGCAACAACATAGACAAAGCCTAAAGGATCCACCA
ATGACCGTAGAGACCTTTTTAGGCTGTTTACAAAAGCAGAAATTACCTCAGTTTATTTCCCATTTACGGGCATTCCAGAT
ATTATTATAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10000.28 Da        Isoelectric Point: 5.1935

>AT201470 WP_110076040.1 NZ_CP074112:c1737726-1737457 [Idiomarina loihiensis]
MKAKDFDTKFDEGADDIIDDLDVKSARRVNQEAKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLRAEAANKPL
KSDTASGAQ

Download         Length: 270 bp

>AT201470 NZ_CP098446:3177343-3177795 [Proteus mirabilis]
ATGAATACGATAAGTGAGAGACTTAGTGCTGAAGATATTGCATTAGCAAAATTAAGTAGCCAAGAGCTATCCGCTGTTAT
GGATATTAATGGCAAAACGCAGAAGCTATCCATTATAGATAAGACGGGTAATAATCATATTGTACAAATACCAAATAGTG
CATTACGCCTAATGATTGAAATTCTTACTCAACTAGGGCAAGGGAATACTGTTAGTATCACACCAATCCATGCTGAGCTA
ACGACACAGGAAGCGGCTGATATACTCAATATGTCCCGTCCTACATTTGTAAAATTATTAGATACACGAGCGATACCCTA
CTCTAGAAAAGGAAATCGTAGGAAAGTTGCTTATGCTGATATTGTTGCTTATAAAAATGAATTGGAGCAAAAACGACTTG
ATGCCCTTGCTGAATTATCGCAATTAGATCAAGAAATGGATATGGGGTATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References