Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE-RHH
Location 1179553..1180109 Replicon chromosome
Accession NZ_CP074112
Organism Idiomarina loihiensis strain SN11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KGF88_RS05620 Protein ID WP_257119983.1
Coordinates 1179553..1179798 (-) Length 82 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag KGF88_RS05625 Protein ID WP_110076941.1
Coordinates 1179822..1180109 (-) Length 96 a.a.

Genomic Context

KGF88_RS05610KGF88_RS05615KGF88_RS05635KGF88_RS05645KGF88_RS05595KGF88_RS05600KGF88_RS05605KGF88_RS05620KGF88_RS05625KGF88_RS05630KGF88_RS05640KGF88_RS05650
Location: 1177721..1178152 (432 bp)
Type: Others
Protein ID: WP_092841881.1
Location: 1178261..1178971 (711 bp)
Type: Others
Protein ID: WP_153827109.1
Location: 1180898..1181245 (348 bp)
Type: Others
Protein ID: WP_228759563.1
Location: 1182264..1183160 (897 bp)
Type: Others
Protein ID: WP_228759562.1
Location: 1175506..1175937 (432 bp)
Type: Others
Protein ID: WP_228759564.1
Location: 1176429..1176896 (468 bp)
Type: Others
Protein ID: WP_153827110.1
Location: 1177217..1177600 (384 bp)
Type: Others
Protein ID: WP_126801850.1
Location: 1179553..1179798 (246 bp)
Type: Toxin
Protein ID: WP_257119983.1
Location: 1179822..1180109 (288 bp)
Type: Antitoxin
Protein ID: WP_110076941.1
Location: 1180214..1180783 (570 bp)
Type: Others
Protein ID: WP_153827108.1
Location: 1181213..1182166 (954 bp)
Type: Others
Protein ID: WP_153827107.1
Location: 1183213..1183725 (513 bp)
Type: Others
Protein ID: WP_194928203.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KGF88_RS05595 (KGF88_05625)1175506..1175937-432WP_228759564.1potassium channel family protein-
KGF88_RS05600 (KGF88_05630)1176429..1176896-468WP_153827110.1GIY-YIG nuclease family protein-
KGF88_RS05605 (KGF88_05635)1177217..1177600-384WP_126801850.1hypothetical protein-
KGF88_RS05610 (KGF88_05640)1177721..1178152+432WP_092841881.1hypothetical protein-
KGF88_RS05615 (KGF88_05645)1178261..1178971+711WP_153827109.1hypothetical protein-
KGF88_RS05620 (KGF88_05650)1179553..1179798-246WP_257119983.1type II toxin-antitoxin system RelE/ParE family toxinToxin
KGF88_RS05625 (KGF88_05655)1179822..1180109-288WP_110076941.1ribbon-helix-helix protein, CopG familyAntitoxin
KGF88_RS05630 (KGF88_05660)1180214..1180783-570WP_153827108.1tellurite resistance methyltransferase TehB-
KGF88_RS05635 (KGF88_05665)1180898..1181245+348WP_228759563.1hexameric tyrosine-coordinated heme protein-
KGF88_RS05640 (KGF88_05670)1181213..1182166-954WP_153827107.1helix-turn-helix domain-containing protein-
KGF88_RS05645 (KGF88_05675)1182264..1183160+897WP_228759562.1MBL fold metallo-hydrolase-
KGF88_RS05650 (KGF88_05680)1183213..1183725-513WP_194928203.1alpha/beta hydrolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9313.56 Da        Isoelectric Point: 5.0348

>T201467 WP_257119983.1 NZ_CP074112:c1179798-1179553 [Idiomarina loihiensis]
IRDREQIYDFIENDNPVAALQLDNQVSSSVANLSEYPEIGREGRVLGTRELVVHANYIVVYDFSKDALRILRILHAAMKW
P

Download         Length: 246 bp

>T201467 NZ_CP098439:c93817-93401 [Salmonella enterica subsp. enterica serovar Typhimurium]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAGCCTGAAGCAGTGCTTAAGAATCT
GGAGCAGGCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGCGCCACCGGTC
CAAAGGCATCGCCACGCCACGTGCAGCTGGTTGACGCGTTCTGCGCCCGTCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGATGCAACCACGGAGGTTAAGGTGGCGCTGCGCCTCGCCGGCACGCCGATCGGTCCAAACGACACGGCGATCGC
CGGGCACGCCATCGCCACCGGGGCAATACTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTGCCTGGACTGGTACTGG
AAGACTGGGCAGGATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10993.19 Da        Isoelectric Point: 9.9158

>AT201467 WP_110076941.1 NZ_CP074112:c1180109-1179822 [Idiomarina loihiensis]
MSDATFTFRVNDELKSEFSKAARSRDRSSAQLLRDFMREYVQQQERLAEHDSWFREQVKQGLDSANAGNLVPAGDVEAKF
AARRALTQRNIDKQR

Download         Length: 288 bp

>AT201467 NZ_CP098439:c94044-93814 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGAGAACCGTATCTATTTTCAAAAATGGCAATAACCGCGCGATCCGTCTGCCCCGCGATCTGGATTTTGAGGGGGTGAG
TGAGCTGGAGATTGTACGGGAAGGGGACAGAATCATTCTGCGTCCCCTCCGCCCGAGCTGGAGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGGCTTTATGACGGAACGCGAGGACGTTGTCTGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References