201339

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 4888278..4889023 Replicon chromosome
Accession NZ_CP074076
Organism Xanthomonas oryzae strain AH28

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag KCI36_RS22905 Protein ID WP_199285672.1
Coordinates 4888278..4888607 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag KCI36_RS22910 Protein ID WP_011407754.1
Coordinates 4888604..4889023 (+) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KCI36_RS22875 (KCI36_22875) 4883409..4884080 + 672 WP_011407759.1 class I SAM-dependent methyltransferase -
KCI36_RS22885 (KCI36_22885) 4884382..4885173 - 792 WP_011407758.1 polysaccharide deacetylase family protein -
KCI36_RS22890 (KCI36_22890) 4885219..4886145 + 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
KCI36_RS22895 (KCI36_22895) 4886477..4886812 + 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
KCI36_RS22900 (KCI36_22900) 4886856..4888175 - 1320 WP_011407756.1 IS701 family transposase -
KCI36_RS22905 (KCI36_22905) 4888278..4888607 + 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
KCI36_RS22910 (KCI36_22910) 4888604..4889023 + 420 WP_011407754.1 macro domain-containing protein Antitoxin
KCI36_RS22915 (KCI36_22915) 4889075..4890043 + 969 WP_011258188.1 IS5-like element ISXo1 family transposase -
KCI36_RS22920 (KCI36_22920) 4890178..4890834 + 657 WP_075246166.1 phosphate phosphatase -
KCI36_RS22925 (KCI36_22925) 4890872..4892107 - 1236 WP_011257570.1 ISL3-like element ISXoo13 family transposase -
KCI36_RS22930 (KCI36_22930) 4892409..4892735 + 327 Protein_4394 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 4886856..4892107 5251


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-108)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T201339 WP_199285672.1 NZ_CP074076:4888278-4888607 [Xanthomonas oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T201339 NZ_CP098338:c5404940-5404557 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT201339 WP_011407754.1 NZ_CP074076:4888604-4889023 [Xanthomonas oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT201339 NZ_CP098338:c5405182-5404940 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References