Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2581335..2582854 Replicon chromosome
Accession NZ_CP074076
Organism Xanthomonas oryzae strain AH28

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag KCI36_RS12275 Protein ID WP_011259680.1
Coordinates 2581931..2582854 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag KCI36_RS12270 Protein ID WP_011409027.1
Coordinates 2581335..2581934 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KCI36_RS12235 (KCI36_12235) 2577017..2577553 - 537 WP_011409032.1 lipocalin family protein -
KCI36_RS23615 2577823..2578290 - 468 WP_181718264.1 hypothetical protein -
KCI36_RS23620 2578271..2578561 - 291 WP_011409031.1 hypothetical protein -
KCI36_RS12255 (KCI36_12255) 2579060..2580091 + 1032 WP_042465093.1 IS630 family transposase -
KCI36_RS12260 (KCI36_12260) 2580073..2580648 - 576 WP_011409029.1 BrxE family protein -
KCI36_RS12265 (KCI36_12265) 2580680..2580970 - 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
KCI36_RS12270 (KCI36_12270) 2581335..2581934 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
KCI36_RS12275 (KCI36_12275) 2581931..2582854 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
KCI36_RS23625 2582934..2583404 - 471 WP_228383551.1 helix-turn-helix domain-containing protein -
KCI36_RS12290 (KCI36_12290) 2583870..2584112 + 243 WP_011409025.1 hypothetical protein -
KCI36_RS12295 (KCI36_12295) 2584564..2585529 - 966 Protein_2344 IS1595-like element ISXo5 family transposase -
KCI36_RS12300 (KCI36_12300) 2585624..2586112 + 489 WP_011409022.1 hypothetical protein -
KCI36_RS12305 (KCI36_12305) 2586129..2586661 - 533 Protein_2346 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T201337 WP_011259680.1 NZ_CP074076:2581931-2582854 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T201337 NZ_CP098338:c4920755-4920471 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGGCCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT201337 WP_011409027.1 NZ_CP074076:2581335-2581934 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT201337 NZ_CP098338:c4920987-4920745 [Klebsiella pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCGGGGGTTAAGGTGAGTCTGGATGACCTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References