201335

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 619715..620065 Replicon chromosome
Accession NZ_CP074076
Organism Xanthomonas oryzae strain AH28

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag KCI36_RS02965 Protein ID WP_011257368.1
Coordinates 619715..619849 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag KCI36_RS02970 Protein ID WP_011407410.1
Coordinates 619913..620065 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KCI36_RS02950 (KCI36_02950) 616729..617673 - 945 WP_041181936.1 MBL fold metallo-hydrolase -
KCI36_RS02955 (KCI36_02955) 617804..619093 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
KCI36_RS02960 (KCI36_02960) 619262..619471 - 210 WP_011407411.1 CsbD family protein -
KCI36_RS02965 (KCI36_02965) 619715..619849 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
KCI36_RS02970 (KCI36_02970) 619913..620065 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
KCI36_RS02975 (KCI36_02975) 620173..621096 - 924 WP_011407409.1 arginase -
KCI36_RS23405 621418..621636 + 219 Protein_560 hypothetical protein -
KCI36_RS02980 (KCI36_02980) 621628..622092 + 465 Protein_561 hypothetical protein -
KCI36_RS23410 622089..622631 + 543 Protein_562 GTPase -
KCI36_RS02995 (KCI36_02995) 623111..623794 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T201335 WP_011257368.1 NZ_CP074076:c619849-619715 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T201335 NZ_CP098338:4201826-4202044 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT201335 WP_011407410.1 NZ_CP074076:c620065-619913 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT201335 NZ_CP098338:4201425-4201799 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References