Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2556263..2556939 Replicon chromosome
Accession NZ_CP074073
Organism Idiomarina loihiensis strain SN11

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KF946_RS12250 Protein ID WP_153850214.1
Coordinates 2556263..2556712 (-) Length 150 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KF946_RS12255 Protein ID WP_153850213.1
Coordinates 2556709..2556939 (-) Length 77 a.a.

Genomic Context

KF946_RS12225KF946_RS12230KF946_RS12240KF946_RS12245KF946_RS12260KF946_RS12210KF946_RS12215KF946_RS12220KF946_RS12235KF946_RS12250KF946_RS12255KF946_RS12265KF946_RS12270KF946_RS12275
Location: 2552944..2554224 (1281 bp)
Type: Others
Protein ID: WP_153850218.1
Location: 2554227..2554934 (708 bp)
Type: Others
Protein ID: WP_153850217.1
Location: 2555639..2555911 (273 bp)
Type: Others
Protein ID: WP_114982302.1
Location: 2555898..2556239 (342 bp)
Type: Others
Protein ID: WP_153850215.1
Location: 2557066..2557722 (657 bp)
Type: Others
Protein ID: WP_110013507.1
Location: 2551339..2551986 (648 bp)
Type: Others
Protein ID: WP_153850221.1
Location: 2552113..2552436 (324 bp)
Type: Others
Protein ID: WP_153850220.1
Location: 2552448..2552741 (294 bp)
Type: Others
Protein ID: WP_153850219.1
Location: 2554931..2555536 (606 bp)
Type: Others
Protein ID: WP_153850216.1
Location: 2556263..2556712 (450 bp)
Type: Toxin
Protein ID: WP_153850214.1
Location: 2556709..2556939 (231 bp)
Type: Antitoxin
Protein ID: WP_153850213.1
Location: 2557800..2559950 (2151 bp)
Type: Others
Protein ID: WP_153850212.1
Location: 2560023..2560493 (471 bp)
Type: Others
Protein ID: WP_153850211.1
Location: 2560493..2561638 (1146 bp)
Type: Others
Protein ID: WP_153850210.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KF946_RS12210 (KF946_12195)2551339..2551986-648WP_153850221.1hypothetical protein-
KF946_RS12215 (KF946_12200)2552113..2552436-324WP_153850220.1HigA family addiction module antitoxin-
KF946_RS12220 (KF946_12205)2552448..2552741-294WP_153850219.1type II toxin-antitoxin system RelE/ParE family toxin-
KF946_RS12225 (KF946_12210)2552944..2554224+1281WP_153850218.1anti-phage deoxyguanosine triphosphatase-
KF946_RS12230 (KF946_12215)2554227..2554934+708WP_153850217.1ZIP family metal transporter-
KF946_RS12235 (KF946_12220)2554931..2555536-606WP_153850216.1hypothetical protein-
KF946_RS12240 (KF946_12225)2555639..2555911+273WP_114982302.1type II toxin-antitoxin system prevent-host-death family antitoxin-
KF946_RS12245 (KF946_12230)2555898..2556239+342WP_153850215.1type II toxin-antitoxin system RelE/ParE family toxin-
KF946_RS12250 (KF946_12235)2556263..2556712-450WP_153850214.1type II toxin-antitoxin system VapC family toxinToxin
KF946_RS12255 (KF946_12240)2556709..2556939-231WP_153850213.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
KF946_RS12260 (KF946_12245)2557066..2557722+657WP_110013507.1epoxyqueuosine reductase QueH-
KF946_RS12265 (KF946_12250)2557800..2559950-2151WP_153850212.1TonB-dependent siderophore receptor-
KF946_RS12270 (KF946_12255)2560023..2560493-471WP_153850211.1hypothetical protein-
KF946_RS12275 (KF946_12260)2560493..2561638-1146WP_153850210.1PepSY-associated TM helix domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-46)


Sequences

Toxin        


Download         Length: 150 a.a.        Molecular weight: 17012.36 Da        Isoelectric Point: 6.9566

>T201334 WP_153850214.1 NZ_CP074073:c2556712-2556263 [Idiomarina loihiensis]
MNLRYMLDTNICIYIMKNRPAYLAPIFDEHSRELCISSVTVMELQYGVENSQQRTTNADKLDSFLARLKILNYDTDAAYH
TALIRHKLKQQGTPIGPYDQMIAGHARCHGLTVVTNNTGEFERVPGLITENWLQQPPQSSINEPTPAYR

Download         Length: 450 bp

>T201334 NZ_CP098338:c2823495-2822173 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8676.68 Da        Isoelectric Point: 4.3575

>AT201334 WP_153850213.1 NZ_CP074073:c2556939-2556709 [Idiomarina loihiensis]
MTKTSLFKSNKTQAVRLPKDVAFSEDVKEVEVLVVGESRIITPAKTSWASWFNGEPTSDDFMVEREQPEEQERDSL

Download         Length: 231 bp

>AT201334 NZ_CP098338:c2823761-2823495 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References