Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2179218..2179489 Replicon chromosome
Accession NZ_CP074052
Organism Escherichia coli strain PD23

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2179348..2179451 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2179218..2179489 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU85_RS10460 2175773..2176435 - 663 WP_000944256.1 exodeoxyribonuclease X -
KFU85_RS10465 2176459..2177115 - 657 WP_000011663.1 carbon-nitrogen hydrolase family protein YobB -
KFU85_RS10470 2177217..2177447 - 231 WP_077516099.1 DNA polymerase III subunit theta -
KFU85_RS10475 2177586..2177960 + 375 WP_000168737.1 CopC domain-containing protein YobA -
KFU85_RS10480 2177964..2178836 + 873 WP_000879323.1 copper homeostasis membrane protein CopD -
KFU85_RS10485 2178849..2179190 + 342 WP_000976472.1 YebY family protein -
- 2179218..2179489 - 272 - - Antitoxin
- 2179348..2179451 + 104 - - Toxin
KFU85_RS10490 2179586..2180242 + 657 WP_000812749.1 protein-serine/threonine phosphatase -
KFU85_RS10495 2180243..2180434 - 192 WP_001296140.1 YebW family protein -
KFU85_RS10500 2180539..2180775 - 237 WP_001295499.1 YebV family protein -
KFU85_RS10505 2180893..2182332 - 1440 WP_024175799.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T201313 NZ_CP074052:2179348-2179451 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT201313 NZ_CP074052:c2179489-2179218 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References